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3-xylene (CID 7929) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Inactive(397)
 
 
Inconclusive(23)
 
 
Unspecified(5)
 
 
Top Targets:
NR LBD PPAR(29)
 
 
 
NR LBD ER(23)
 
 
 
NR LBD AR(23)
 
 
 
NR LBD VDR(14)
 
 
 
NR LBD Fxr(14)
 
 
BioAssay Types:
Confirmatory(336)
 
 
 
 
Summary(72)
 
 
 
Literature(7)
 
 
 
 
BioActivity Types:
Potency(353)
 
 
 
 
IC50(2)
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 246    Data Row: 433   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103196116]
IC50 0.002Inhibition of acetylcholinesterase. [AID32248, Type: Literature]
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2
[SID144209254]
Potency-Replicate_1 1.3391qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID144209254]
Ratio Potency (uM) 2.38134qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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4
[SID103196116]
IC50 4.9IC50 against acetylcholinesterase; value ranges from 1-4900 nM. [AID32280, Type: Literature]
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5
[SID144209254]
Potency-Replicate_1 26.4751qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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6
[SID48414639]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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7
[SID48414639]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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8
[SID48414639]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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9
[SID103196116]
Kd 364Dissociation constant against T4 lysozyme mutant L99A [AID238119, Type: Literature]Lysozyme [gi:126605]
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10
[SID103196116]
LC50 3.54813e+08Toxicity determined using Konemann's Industrial Pollutants Toxicity Test [AID162229, Type: Literature]
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11
[SID103196116]
Octanol-water partition coefficient, log P of the compound [AID603957, Type: Literature]
View
12
[SID17388890]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
13
[SID103196116]
Partition coefficient (logP) [AID24226, Type: Literature]
View
14
[SID17388890]
Potency 7.4978qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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15
[SID144213520]
Potency-Replicate_1 21.8724qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
16
[SID144213520]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
17
[SID144213520]
Ratio Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
18
[SID144213520]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
19
[SID144213520]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
20
[SID144209254]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
21
[SID144209254]
ER Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
22
[SID144213520]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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23
[SID144213520]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
24
[SID144213520]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
25
[SID144209254]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
26
[SID144209254]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
27
[SID144209254]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
28
[SID144207490]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
29
[SID144207490]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
30
[SID144207490]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
31
[SID17388890]
Potency qHTS assay for small molecule antagonists of glucocorticoid receptor signaling [AID588533, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
32
[SID17388890]
Potency qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
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33
[SID17388890]
Potency qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
View
34
[SID17388890]
Potency qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling [AID588546, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
View
35
[SID17388890]
Potency qHTS assay for small molecule antagonists of farnesoid X receptor signaling [AID588526, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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36
[SID17388890]
Potency qHTS assay for small molecule agonists of farnesoid X receptor signaling [AID588527, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
37
[SID144207490]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743217, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
38
[SID144207490]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743220, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
39
[SID144207490]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743239, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
40
[SID144207490]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
41
[SID144209254]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743239, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
42
[SID144209254]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
43
[SID144209254]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743217, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
44
[SID144209254]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743220, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
45
[SID144213520]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743217, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
46
[SID144213520]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743220, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
47
[SID144213520]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743239, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
48
[SID144213520]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
49
[SID17388890]
Potency-Replicate_1 qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
View
50
[SID17388890]
Potency qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
View