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BioActivity Data for Compound 2-(trimethylammonio)ethyl methacrylate (CID 78738)

BioActivity Outcomes:
Active(4)
 
 
Inactive(111)
 
 
Inconclusive(10)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD AR(9)
 
 
NR LBD ER(9)
 
 
NR LBD TR(7)
 
 
 
NR LBD Fxr(6)
 
 
BioAssay Types:
Confirmatory(93)
 
 
 
 
Summary(24)
 
 
 
 
BioAssay Categories:
Toxicity(15)
 
 
 
 
 
BioActivity Types:
Potency(111)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 118    Data Row: 126   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209762]
Potency-Replicate_1 2.1795qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743191, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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2
[SID144209762]
Potency-Replicate_1 38.4139qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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3
[SID144209762]
Potency-Replicate_1 60.882qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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4
[SID144209762]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743199, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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5
[SID26757582]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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6
[SID144209762]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells [AID720680, Type: confirmatory]
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7
[SID144209762]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cell free culture [AID720681, Type: confirmatory]
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8
[SID144209762]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell free culture [AID720682, Type: confirmatory]
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9
[SID144209762]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cell free culture [AID720683, Type: confirmatory]
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10
[SID144209762]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cell free culture [AID720684, Type: confirmatory]
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11
[SID144209762]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cell free culture [AID720685, Type: confirmatory]
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12
[SID144209762]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cell free culture [AID720686, Type: confirmatory]
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13
[SID144209762]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cells [AID720687, Type: confirmatory]
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14
[SID144209762]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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15
[SID144209762]
Ratio Potency (uM) qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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16
[SID144209762]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cells [AID720674, Type: confirmatory]
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17
[SID144209762]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cells [AID720675, Type: confirmatory]
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18
[SID144209762]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells [AID720678, Type: confirmatory]
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19
[SID144209762]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cells [AID720679, Type: confirmatory]
View
20
[SID144209762]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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