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12-HYDROXYOCTADECANOIC ACID (CID 7789) - Compound BioActivity Data
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BioActivity Outcomes:
Active(16)
 
 
Inactive(154)
 
 
Inconclusive(51)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
 
NR LBD AR(16)
 
 
 
NR LBD ER(16)
 
 
 
NR LBD Fxr(10)
 
 
 
 
NR LBD VDR(10)
 
 
 
BioAssay Types:
Confirmatory(155)
 
 
 
 
Summary(48)
 
 
 
 
Literature(1)
 
 
BioActivity Types:
Potency(191)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 129    Data Row: 223   Total Pages: 12   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213352]
Potency-Replicate_1 10.9635qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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2
[SID144213352]
Ratio Potency (uM) 15.4864qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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3
[SID144213352]
Potency-Replicate_1 19.4962qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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4
[SID144208690]
Potency-Replicate_1 19.5534qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
View
5
[SID144208690]
Potency-Replicate_1 19.5534qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
View
6
[SID144208690]
Ratio Potency (uM) 19.5534qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
7
[SID144213352]
Ratio Potency (uM) 21.8751qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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8
[SID144213352]
Potency-Replicate_1 21.8751qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
9
[SID144208690]
Potency-Replicate_1 21.9393qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
10
[SID144208690]
Potency-Replicate_1 21.9393qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
View
11
[SID144213352]
Ratio Potency (uM) 25.7785qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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12
[SID26757769]
Potency 31.6228qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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13
[SID144213352]
Potency-Replicate_1 34.6697qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743217, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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14
[SID144213352]
Potency-Replicate_1 48.5577qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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15
[SID144213352]
Potency-Replicate_1 54.4827qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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16
[SID144213352]
Potency-Replicate_1 54.4827qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
17
[SID103242611]
In vitro inhibitory concentration measured against U-46,619 (1 uM) induced aggregation of washed platelets (WP) in rabbit; N-Negative [AID167832, Type: Literature]
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18
[SID26757769]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
19
[SID144213352]
Potency-Replicate_1 1.9496qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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20
[SID144208690]
Potency-Replicate_1 21.9393qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View