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3-(2,5-Dimethyl-pyrrol-1-yl)-4-hydroxy-benzoic acid (CID 776830) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Inactive(8)
 
 
Top Targets:
Peptidase S29(3)
 
 
PTPc(2)
 
 
DSPc(2)
 
 
RNase H(1)
 
 
BioAssay Types:
Screening(9)
 
 
 
Confirmatory(6)
 
 
 
BioActivity Types:
IC50(4)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 16    Data Row: 16   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID163601152]
HDA (HCV NS3h) Average IC50 50.4Fluorescence polarization based biochemical confirmatory assay of ChemBridge compounds to identify inhibitors of hepatitis C non-structural protein 3 helicase [AID743264, Type: confirmatory]NS3 [Hepatitis C virus] [gi:125541954]
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2
[SID10322021]
Activity Assay, Human PTPN7 [AID401, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 1 [Homo sapiens] [gi:315221140]
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3
[SID17463777]
IC50 HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target [AID521, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
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4
[SID163601152]
Fluorescence polarization based primary biochemical high throughput screening assay of ChemBridge compounds to identify inhibitors of hepatitis C virus non-structural protein 3 helicase [AID687043, Type: screening]NS3 [Hepatitis C virus] [gi:125541954]
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5
[SID163601152]
Fluorescence polarization based confirmation biochemical high throughput screening assay of ChemBridge compounds to identify inhibitors of hepatitis C non-structural protein 3 helicase [AID720485, Type: screening]NS3 [Hepatitis C virus] [gi:125541954]
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6
[SID163601152]
Biochemical high throughput counterscreening assay of selected ChemBridge compounds for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3): fluorescence polarization based assay to identify compounds that inhibit the ability of E. coli ssDNA binding protein to bind DNA [AID720486, Type: screening]
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7
[SID163601152]
Fluorescence-based counterscreen assay for HCV NS3 helicase inhibitors of a ChemBridge library: biochemical high-throughput screening assay to identify compounds that enhance or quench Cy5 fluorescence [AID720488, Type: screening]
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8
[SID10322021]
Activity Assay, Human PTPRR [AID405, Type: screening]receptor-type tyrosine-protein phosphatase R isoform 1 precursor [Homo sapiens] [gi:4506325]
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9
[SID17463777]
HTS Colorimetric assay for the identification of compounds that inhibit VHR1 [AID1992, Type: screening]dual specificity protein phosphatase 3 [Homo sapiens] [gi:4758208]
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10
[SID17463777]
IC50 MKP-3 in vitro HTS assay [AID425, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
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11
[SID163601152]
Fluorescence-based confirmation counterscreen assay for HCV NS3 helicase inhibitors of a ChemBridge library: biochemical high-throughput screening assay to identify compounds that enhance or quench fluorescence of a Cy5-DNA-NS3h complex [AID720489, Type: screening]
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12
[SID163601152]
Fluorescence-based counterscreen assay for HCV NS3 helicase inhibitors of selected ChemBridge compounds: biochemical high-throughput screening assay to identify compounds that enhance or quench fluorescence of a Cy5-labeled oligonucleotide bound to E. coli SSB [AID720487, Type: screening]
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13
[SID49931424]
High Throughput Screen of 100,000 compound library to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1949, Type: confirmatory]
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14
[SID49931424]
A High Throughput Screening Assay for Inhibitors of Bacterial Motility in Vibrio cholerae [AID588778, Type: other]
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15
[SID8098274]
HIV-1 RNase H Inhibition [AID372, Type: screening]Chain A, Solution Structure Of The Rnase H Domain Of The Hiv-1 Reverse Transcriptase In The Presence Of Magnesium [gi:28949057]
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16
[SID17463777]
IC50 High Throughput Screening Assay for Hsp70 Inhibitors [AID583, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
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