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2-{[2-(4-chlorophenyl)ethyl]amino}benzoic acid (CID 7721337) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(4)
 
 
Top Targets:
Rac1 like(2)
 
 
 
Ras like GTPa..(2)
 
 
Rab2(1)
 
 
GST C Mu(1)
 
 
Rab7(1)
 
 
BioAssay Types:
Confirmatory(9)
 
 
 
BioActivity Types:
EC50(9)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 9    Data Row: 9   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56431766]
EC50_MICROM 0.3392Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype [AID1336, Type: confirmatory]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
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2
[SID56431766]
EC50_MICROM 0.7408Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID1337, Type: confirmatory]Ras-related protein Rab-2A [gi:46577642]
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3
[SID56431766]
EC50_MICROM 0.8851Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant [AID1333, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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4
[SID56431766]
EC50_MICROM 1.523Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype [AID1340, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
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5
[SID56431766]
EC50_MICROM 1.534Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID1334, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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6
[SID56431766]
EC50_MICROM Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays [AID1769, Type: confirmatory]glutathione S-transferase, partial [Homo sapiens] [gi:31933]
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7
[SID56431766]
EC50_MICROM Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID1335, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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8
[SID56431766]
EC50_MICROM Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant [AID1341, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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9
[SID56431766]
EC50_MICROM Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant [AID1339, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
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