ZINC00244844 (CID 767276) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(11)
 
 
Top Targets:
HSPA1-2 6-8-l..(6)
 
 
ABCC CFTR1(1)
 
 
Aldo ket red(1)
 
 
BRLZ(1)
 
 
HSPA5-like NB..(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 11   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): yellow fluorescent protein (YFP) quenching assay to assess changes in trafficking of DeltaF508-CFTR [AID651992, Type: other]CFTR gene product [Homo sapiens] [gi:90421313]
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2
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): yellow fluorescent protein (YFP) quenching assay to assess changes in trafficking of DeltaF508-CFTR [AID651992, Type: other]CFTR gene product [Homo sapiens] [gi:90421313]
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3
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): fluorescence-based biochemical quantitative polymerase chain reaction assay to assess Hsp70 gene expression changes [AID651945, Type: other]heat shock 70kDa protein 1A [Homo sapiens] [gi:119623933]
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4
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): fluorescence-based biochemical quantitative polymerase chain reaction assay to assess Hsp70 gene expression changes [AID651945, Type: other]heat shock 70kDa protein 1A [Homo sapiens] [gi:119623933]
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5
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): chemiluminescence-based biochemical western blot assay for transcriptional activators of heat shock protein Hsp70 [AID651948, Type: other]heat shock 70kDa protein 1A [Homo sapiens] [gi:119623933]
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6
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): chemiluminescence-based biochemical western blot assay for transcriptional activators of heat shock protein Hsp70 [AID651948, Type: other]heat shock 70kDa protein 1A [Homo sapiens] [gi:119623933]
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7
[SID152186720]
 Late stage assay for the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70). Luminescence-based-cell-based high-throughput dose response assay for Hsp70 activators [AID651950, Type: other]Heat shock 70kDa protein 1A [Homo sapiens] [gi:12803275]
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8
[SID152186720]
 Late stage assay for the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70). Luminescence-based-cell-based high-throughput dose response assay for Hsp70 activators [AID651950, Type: other]Heat shock 70kDa protein 1A [Homo sapiens] [gi:12803275]
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9
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): fluorescence-based cell-based microscopic assay to assess aggregation of polyQ35 in C. elegans larvae [AID651963, Type: other]Protein HSP-70 [Caenorhabditis elegans] [gi:3874268]
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10
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): fluorescence-based biochemical quantitative polymerase chain reaction assay to assess gene expression changes in downstream target genes [AID651964_2, Type: other]Gclm gene product [Mus musculus] [gi:6680019]
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11
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): fluorescence-based biochemical quantitative polymerase chain reaction assay to assess gene expression changes in downstream target genes [AID651964_5, Type: other]Hmox1 gene product [Mus musculus] [gi:6754212]
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12
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): fluorescence-based biochemical quantitative polymerase chain reaction assay to assess gene expression changes in downstream target genes [AID651964_4, Type: other]Heat shock protein 5 [Mus musculus] [gi:29748016]
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13
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): fluorescence-based biochemical quantitative polymerase chain reaction assay to assess gene expression changes in downstream target genes [AID651964, Type: other]Hspa1a gene product [Mus musculus] [gi:124339829]
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14
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): fluorescence-based biochemical quantitative polymerase chain reaction assay to assess gene expression changes in downstream target genes [AID651964_1, Type: other]Hspa1a gene product [Mus musculus] [gi:124339829]
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15
[SID152186720]
 Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): fluorescence-based biochemical quantitative polymerase chain reaction assay to assess gene expression changes in downstream target genes [AID651964_3, Type: other]Ddit3 gene product [Mus musculus] [gi:160707929]
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