1-benzylpiperazine (CID 75994) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Inactive(5)
 
 
Unspecified(5)
 
 
Top Targets:
7TM GPCR Srsx(1)
 
 
CASc(1)
 
 
Firefly Luc l..(1)
 
 
Glutaminase(1)
 
 
HpcH HpaI(1)
 
 
BioAssay Types:
Literature(6)
 
 
 
Confirmatory(5)
 
 
BioActivity Types:
Potency(5)
 
 
Ki(3)
 
 
 
EC50(1)
 
 
IC50(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 12    Data Row: 12   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103336926]
Ki 10.48Binding affinity towards sigma receptor in guinea pig brain membranes using [3H]DTG as radioligand [AID204444, Type: Literature]
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2
[SID48415389]
 DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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3
[SID103336926]
Ki 10Binding affinity against 5-hydroxytryptamine 2 receptor in rat using [3H]ketanserin as radioligand [AID5225, Type: Literature]
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4
[SID103336926]
Ki 10Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand [AID4755, Type: Literature]5-hydroxytryptamine receptor 2C [gi:112817]
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5
[SID103336926]
Ki 10Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand [AID4755, Type: Literature]5-hydroxytryptamine receptor 2C [gi:112817]
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6
[SID103336926]
EC50 50Activation of N-terminal His6-tagged recombinant procaspase-3 expressed in Escherichia coli assessed as hydrolysis of acetyl-DEVD-p-nitroanilide after 2 hrs by SDS-PAGE [AID503695, Type: Literature]
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7
[SID103336926]
IC50 100Activation of procaspase-3-mediated human HL60 cell death after 72 hrs by MTS/PMS assay [AID503719, Type: Literature]Caspase-3 [gi:77416852]
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8
[SID103336926]
IC50 100Activation of procaspase-3-mediated human HL60 cell death after 72 hrs by MTS/PMS assay [AID503719, Type: Literature]Caspase-3 [gi:77416852]
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9
[SID103336926]
IC50 100Activation of procaspase-3-mediated human HL60 cell death after 72 hrs by MTS/PMS assay [AID503719, Type: Literature]Caspase-3 [gi:77416852]
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10
[SID103336926]
IC50 100Activation of procaspase-3-mediated human HL60 cell death after 72 hrs by MTS/PMS assay [AID503719, Type: Literature]Caspase-3 [gi:77416852]
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11
[SID103904031]
 Wombat Data for BeliefDocking [AID493017, Type: Literature] [geneid:10280]
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12
[SID103904031]
 Wombat Data for BeliefDocking [AID493017, Type: Literature] [geneid:10280]
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13
[SID124954087]
Potency qHTS of GLP-1 Receptor Agonists [AID624172, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
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14
[SID124954087]
Potency qHTS of GLP-1 Receptor Agonists [AID624172, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
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15
[SID124954087]
Potency qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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16
[SID124954087]
Potency Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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17
[SID124954087]
Potency qHTS of Trypanosoma Brucei Inhibitors [AID624173, Type: confirmatory]hypothetical protein, conserved [Trypanosoma brucei] [gi:62359610]
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18
[SID124954087]
Potency qHTS for Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in Human Glioma: qHTS [AID602332, Type: confirmatory]heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) [Homo sapiens] [gi:168984549]
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