STK200399 (CID 756156) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(31)
 
 
Inactive(686)
 
 
Inconclusive(22)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(22)
 
 
 
alkPPc(16)
 
 
Bcl-2 like(11)
 
 
7TM GPCR Srsx(11)
 
 
Peptidase C48(11)
 
 
 
BioAssay Types:
Screening(499)
 
 
 
 
Confirmatory(224)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(143)
 
 
 
 
 
IC50(50)
 
 
 
 
EC50(13)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 740    Data Row: 740   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID7972441]
Potency 0.4467qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]RAB9A gene product [Homo sapiens] [gi:4759012]
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2
[SID7972441]
Potency 0.631qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]NPC1 gene product [Homo sapiens] [gi:255652944]
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3
[SID7972441]
Potency 1.1995qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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4
[SID7972441]
EC50 2.355Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]NFKB1 gene product [Homo sapiens] [gi:34577122]
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5
[SID7972441]
EC50 2.355Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]NFKB1 gene product [Homo sapiens] [gi:34577122]
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6
[SID7972441]
EC50 2.355Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]NFKB1 gene product [Homo sapiens] [gi:34577122]
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7
[SID7972441]
EC50 2.355Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]NFKB1 gene product [Homo sapiens] [gi:34577122]
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8
[SID7972441]
IC50 2.65Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 7 (SENP7) using a Luminescent assay [AID488904, Type: confirmatory]SUMO1/sentrin specific peptidase 7 [Homo sapiens] [gi:120538355]
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9
[SID7972441]
IC50 3.19Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay [AID488921, Type: confirmatory]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
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10
[SID7972441]
IC50 3.19Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay [AID488901, Type: confirmatory]CASP3 gene product [Homo sapiens] [gi:14790119]
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11
[SID7972441]
IC50 3.19Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay [AID488901, Type: confirmatory]CASP3 gene product [Homo sapiens] [gi:14790119]
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12
[SID7972441]
IC50 3.19Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay [AID488901, Type: confirmatory]CASP3 gene product [Homo sapiens] [gi:14790119]
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13
[SID7972441]
IC50 3.19Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay [AID488901, Type: confirmatory]CASP3 gene product [Homo sapiens] [gi:14790119]
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14
[SID7972441]
IC50 8.03Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay [AID488903, Type: confirmatory]SENP8 gene product [Homo sapiens] [gi:262118306]
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15
[SID7972441]
Potency 12.5893qHTS Assay for Inhibitors of Firefly Luciferase [AID411, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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16
[SID7972441]
Potency 25.1189qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta- Hydroxysteroid Dehydrogenase Type 10) Bound [gi:122921310]
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17
[SID7972441]
Potency 70.7946qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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18
[SID7972441]
 Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
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19
[SID7972441]
 Counter Screen for Luciferase-based Primary Inhibition Assays [AID1006, Type: screening]
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20
[SID7972441]
 MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
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21
[SID7972441]
 Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) [AID2796, Type: screening]aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003]
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22
[SID7972441]
 Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) [AID2796, Type: screening]aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003]
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23
[SID7972441]
 Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) [AID2796, Type: screening]aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003]
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24
[SID7972441]
 Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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25
[SID7972441]
 A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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26
[SID7972441]
 Primary screen for compounds that activate Alzheimer's amyloid precursor [AID1276, Type: screening]amyloid precursor protein; APP [Homo sapiens] [gi:257380]
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27
[SID7972441]
 Primary screen for compounds that activate Alzheimer's amyloid precursor [AID1276, Type: screening]amyloid precursor protein; APP [Homo sapiens] [gi:257380]
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28
[SID7972441]
 Primary screen for compounds that activate Alzheimer's amyloid precursor [AID1276, Type: screening]amyloid precursor protein; APP [Homo sapiens] [gi:257380]
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29
[SID7972441]
 Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) [AID695, Type: confirmatory]NR5A1 gene product [Homo sapiens] [gi:20070193]
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30
[SID7972441]
 Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) [AID695, Type: confirmatory]NR5A1 gene product [Homo sapiens] [gi:20070193]
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31
[SID7972441]
 Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) [AID695, Type: confirmatory]NR5A1 gene product [Homo sapiens] [gi:20070193]
View
32
[SID7972441]
 uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7) [AID434973, Type: screening]SUMO1/sentrin specific peptidase 7 [Homo sapiens] [gi:120538355]
View
33
[SID7972441]
 uHTS identification of SKN-1 Inhibitors in a fluoresence assay [AID624304, Type: screening]Protein SKN-1, isoform b [Caenorhabditis elegans] [gi:25148072]
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34
[SID7972441]
 HTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 8 (SENP8) [AID2540, Type: screening]SENP8 gene product [Homo sapiens] [gi:262118306]
View
35
[SID7972441]
 Single concentration confirmation of uHTS for inhibitors of Sentrin-specific protease 7 (SENP7) using a Luminescent assay [AID488917, Type: screening]SUMO1/sentrin specific peptidase 7 [Homo sapiens] [gi:120538355]
View
36
[SID7972441]
 Luminescence-based cell-based primary high throughput screening assay to identify agonists of the DAF-12 from the parasite H. glycines (hgDAF-12). [AID687014, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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37
[SID7972441]
 High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]NFKB1 gene product [Homo sapiens] [gi:34577122]
View
38
[SID7972441]
 High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]NFKB1 gene product [Homo sapiens] [gi:34577122]
View
39
[SID7972441]
 High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]NFKB1 gene product [Homo sapiens] [gi:34577122]
View
40
[SID7972441]
 High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]NFKB1 gene product [Homo sapiens] [gi:34577122]
View
41
[SID7972441]
 Dose-response cell-based assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID681, Type: confirmatory]Nuclear receptor ROR-alpha [gi:548814]
View
42
[SID7972441]
 Dose-response cell-based assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID681, Type: confirmatory]Nuclear receptor ROR-alpha [gi:548814]
View
43
[SID7972441]
 Dose-response cell-based assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID681, Type: confirmatory]Nuclear receptor ROR-alpha [gi:548814]
View
44
[SID7972441]
 Dose-response cell-based assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID681, Type: confirmatory]Nuclear receptor ROR-alpha [gi:548814]
View
45
[SID7972441]
 Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID560, Type: screening]Nuclear receptor ROR-alpha [gi:548814]
View
46
[SID7972441]
 Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID560, Type: screening]Nuclear receptor ROR-alpha [gi:548814]
View
47
[SID7972441]
 Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID560, Type: screening]Nuclear receptor ROR-alpha [gi:548814]
View
48
[SID7972441]
 Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID560, Type: screening]Nuclear receptor ROR-alpha [gi:548814]
View
49
[SID7972441]
 Confirmation cell-based high throughput screening assay to measure STAT1 activation [AID1262, Type: screening]signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens] [gi:6274552]
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50
[SID7972441]
 Confirmation cell-based high throughput screening assay to measure STAT1 activation [AID1262, Type: screening]signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens] [gi:6274552]
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