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ZINC05168882 (CID 7532476) - Compound BioActivity Data
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BioActivity Outcomes:
Active(19)
 
 
Inactive(681)
 
 
Inconclusive(12)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
 
7TM GPCR Srsx(17)
 
 
Bcl-2 like(17)
 
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(476)
 
 
 
 
Confirmatory(213)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(142)
 
 
 
 
IC50(38)
 
 
EC50(24)
 
 
 
AC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 646    Data Row: 713   Total Pages: 36   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24815803]
EC50_MICROM 5.17Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-XL. [AID1322, Type: confirmatory]bcl-xL [Homo sapiens] [gi:510901]
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2
[SID24815803]
EC50_MICROM 5.76Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Mcl-1. [AID1329, Type: confirmatory]Mcl-1 [Homo sapiens] [gi:7582271]
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3
[SID24815803]
EC50_MICROM 7.843Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays [AID1769, Type: confirmatory]glutathione S-transferase, partial [Homo sapiens] [gi:31933]
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4
[SID24815803]
EC50_MICROM 7.89Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. [AID1330, Type: confirmatory]Bcl-w [Homo sapiens] [gi:1572493]
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5
[SID24815803]
AC50_uM 16.56ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_Dose_CherryPick_Activity [AID651703, Type: confirmatory]transforming acidic coiled-coil-containing protein 3 [Homo sapiens] [gi:5454102]
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6
[SID24815803]
AC50_uM 16.56ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_Dose_CherryPick_Activity [AID651703, Type: confirmatory]aryl hydrocarbon receptor nuclear translocator [Homo sapiens] [gi:2702319]
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7
[SID24815803]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID759, Type: screening]ras protein, partial [Homo sapiens] [gi:190938]
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8
[SID24815803]
qHTS Assay for Inhibitors of the Six1/Eya2 Interaction [AID651725, Type: screening]six1 [Homo sapiens] [gi:1246761]
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9
[SID24815803]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype [AID758, Type: screening]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
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10
[SID24815803]
qHTS Assay for Inhibitors of the CtBP/E1A Interaction [AID651724, Type: screening]CtBP interacting protein CtIP [Homo sapiens] [gi:1730321]
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11
[SID24815803]
ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_SinglePoint_HTS_Activity [AID623870, Type: screening]aryl hydrocarbon receptor nuclear translocator [Homo sapiens] [gi:2702319]
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12
[SID24815803]
Primary biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase [AID1527, Type: screening]metallo beta-lactamase [Pseudomonas aeruginosa] [gi:7381449]
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13
[SID24815803]
Epi-absorbance-based confirmation assay for common VIM-2 and IMP-1 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase. [AID2187, Type: screening]metallo beta-lactamase [Pseudomonas aeruginosa] [gi:7381449]
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14
[SID24815803]
Antagonist of Human D 1 Dopamine Receptor: qHTS [AID504652, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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15
[SID24815803]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype [AID757, Type: screening]Rac1 protein [Homo sapiens] [gi:8574038]
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16
[SID24815803]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant [AID764, Type: screening]Rac1 protein [Homo sapiens] [gi:8574038]
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17
[SID24815803]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID761, Type: screening]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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18
[SID24815803]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID760, Type: screening]Ras-related protein Rab-2A [gi:46577642]
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19
[SID24815803]
ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_SinglePoint_HTS_Activity [AID623870, Type: screening]transforming acidic coiled-coil-containing protein 3 [Homo sapiens] [gi:5454102]
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20
[SID24815803]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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