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Glycerol (CID 753) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(636)
 
 
Inconclusive(30)
 
 
Unspecified(13)
 
 
Top Targets:
NR LBD PPAR(28)
 
 
 
NR LBD ER(25)
 
 
NR LBD AR(25)
 
 
 
NR LBD TR(19)
 
 
 
NR LBD GR(16)
 
 
 
BioAssay Types:
Confirmatory(507)
 
 
 
 
Literature(76)
 
 
 
 
Summary(63)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(479)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 291    Data Row: 681   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210464]
Potency-Replicate_1 19.4843qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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2
[SID48416063]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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3
[SID103192728]
Partition coefficient (logP) [AID26811, Type: Literature]
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4
[SID103192728]
Compound was tested for inhibition of Human acrosin by polyols [AID30433, Type: Literature]
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5
[SID103192728]
Eye irritation potential accessed using Draize in vivo rabbit eye irritation test [AID167125, Type: Literature]
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6
[SID103192728]
The capillary permeability of radioligand was measured in Rat brain [AID189629, Type: Literature]
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7
[SID103192728]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature]
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8
[SID103192728]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents [AID588212, Type: Literature]
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9
[SID103192728]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents [AID588213, Type: Literature]
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10
[SID103192728]
Literature-mined public compounds from Kruhlak et al phospholipidosis modelling dataset [AID588220, Type: Literature]
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11
[SID17388987]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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12
[SID17389867]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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13
[SID29215106]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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14
[SID103192728]
Inhibition of human recombinant KAT1 expressed in Sf9 cells assessed as decrease in enzyme activity at 25 % ligand concentration [AID349603, Type: Literature]Kynurenine--oxoglutarate transaminase 1 [gi:46396284]
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15
[SID103192728]
TP_TRANSPORTER: Daunomycin accumulation in Caco-2 cells [AID681134, Type: other]Multidrug resistance protein 1 [gi:238054374]
View
16
[SID144204594]
Potency-Replicate_1 6.6824qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
17
[SID144204594]
Potency-Replicate_1 26.6032qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
18
[SID144204594]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
19
[SID144204594]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway [AID720691, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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20
[SID144204594]
Ratio Potency (uM) qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
View
21
[SID144204594]
AR Potency (uM) qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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22
[SID144204594]
Ratio Potency (uM) qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
23
[SID144204594]
ER Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
24
[SID144204594]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
25
[SID144210464]
ER Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
26
[SID144210464]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
27
[SID144210464]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
28
[SID144210464]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
29
[SID144210464]
Ratio Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
30
[SID144210464]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
31
[SID144210464]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
32
[SID144210464]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
33
[SID144210464]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
34
[SID144210464]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
35
[SID144209275]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
36
[SID144209275]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
37
[SID144209275]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
38
[SID144209275]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720719, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
39
[SID144209275]
qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720725, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
40
[SID144210464]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway [AID720691, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
41
[SID144210464]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway [AID720692, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
42
[SID17389867]
Potency qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
View
43
[SID17388987]
Potency qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
View
44
[SID17389867]
Potency qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling [AID588546, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
View
45
[SID17388987]
Potency qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling [AID588546, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
View
46
[SID17389867]
Potency qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
View
47
[SID17388987]
Potency qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
View
48
[SID17388987]
Potency qHTS assay for small molecule antagonists of farnesoid X receptor signaling [AID588526, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
49
[SID17388987]
Potency qHTS assay for small molecule agonists of farnesoid X receptor signaling [AID588527, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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50
[SID17389867]
Potency qHTS assay for small molecule antagonists of farnesoid X receptor signaling [AID588526, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View