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BioActivity Data for Compound nitrobenzene (CID 7416)

BioActivity Outcomes:
Active(7)
 
 
Inactive(516)
 
 
Inconclusive(21)
 
 
Unspecified(129)
 
 
Top Targets:
NR LBD PPAR(28)
 
 
 
NR LBD ER(25)
 
 
 
NR LBD AR(25)
 
 
NR LBD TR(17)
 
 
 
NR LBD GR(16)
 
 
 
BioAssay Types:
Confirmatory(387)
 
 
 
 
Literature(101)
 
 
 
 
Summary(63)
 
 
 
Screening(2)
 
 
BioAssay Categories:
In vivo(90)
 
 
Biochemical(6)
 
 
 
Toxicity(149)
 
 
 
 
 
ADME(18)
 
 
BioActivity Types:
Potency(397)
 
 
 
 
IC50(1)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 407    Data Row: 673   Total Pages: 34   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389793]
Potency 31.6228qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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2
[SID48414135]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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3
[SID48415021]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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4
[SID75025]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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5
[SID48414135]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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6
[SID48414135]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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7
[SID48414135]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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8
[SID103179177]
Ki 274.1Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis [AID617312, Type: Literature]Glutathione reductase, mitochondrial [gi:14916998]
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9
[SID103179177]
IC50 546.8Inhibition of human erythrocyte Glutathione reductase [AID617311, Type: Literature]Glutathione reductase, mitochondrial [gi:14916998]
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10
[SID103179177]
LC50 545758Toxicity determined using Golden Orfe Fish Test [AID101345, Type: Literature]
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11
[SID103179177]
Inhibition of Rana pipiens muscle activity. [AID168703, Type: Literature]
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12
[SID17389793]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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13
[SID144204678]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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14
[SID103179177]
Binding affinity to Enterobacteria phage T4 lysozyme L99A/M102H double mutant expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 1 mM at pH 3.05 by circular dichroism analysis [AID728438, Type: Literature]
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15
[SID103179177]
DrugMatrix: Regimen: Daily Repeat; Time: 3 day; Dose: High; Vehicle: .5 % cmc; Route: oral gavage | Dataset: Hematology; Assay: MCV (Ery. Mean Corpuscular Volume); Study_ID: R040818 [AID925451, Type: other]
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16
[SID103179177]
DrugMatrix: Regimen: Daily Repeat; Time: 3 day; Dose: High; Vehicle: .5 % cmc; Route: oral gavage | Dataset: Hematology; Assay: MCHC (Ery. Mean Corpuscular HGB Concentration); Study_ID: R040818 [AID925452, Type: other]
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17
[SID103179177]
DrugMatrix: Regimen: Daily Repeat; Time: 3 day; Dose: High; Vehicle: .5 % cmc; Route: oral gavage | Dataset: Hematology; Assay: PLAT (Platelets); Study_ID: R040818 [AID925453, Type: other]
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18
[SID103179177]
DrugMatrix: Regimen: Daily Repeat; Time: 3 day; Dose: High; Vehicle: .5 % cmc; Route: oral gavage | Dataset: Hematology; Assay: BASOLE (Basophils/Leukocytes); Study_ID: R040818 [AID925454, Type: other]
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19
[SID103179177]
DrugMatrix: Regimen: Daily Repeat; Time: 3 day; Dose: High; Vehicle: .5 % cmc; Route: oral gavage | Dataset: Hematology; Assay: WBC (Leukocytes); Study_ID: R040818 [AID925455, Type: other]
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20
[SID103179177]
DrugMatrix: Regimen: Daily Repeat; Time: 3 day; Dose: High; Vehicle: .5 % cmc; Route: oral gavage | Dataset: Hematology; Assay: HGB (Hemoglobin); Study_ID: R040818 [AID925456, Type: other]
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