Bookmark and Share
acetophenone (CID 7410) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(167)
 
 
Inconclusive(13)
 
 
Unspecified(24)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
 
NR LBD AR(14)
 
 
 
NR LBD ER(14)
 
 
NR LBD Fxr(8)
 
 
 
NR LBD VDR(8)
 
 
BioAssay Types:
Confirmatory(124)
 
 
 
Summary(48)
 
 
 
Literature(26)
 
 
 
BioActivity Types:
Potency(160)
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 119    Data Row: 205   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID48415020]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
View
2
[SID103179218]
IC50 100Inhibition of GSK3-beta by liquid scintillation counting [AID452111, Type: Literature]
View
3
[SID103179218]
IC50 850Inhibition of mushroom tyrosinase [AID327624, Type: Literature]Polyphenol oxidase 2 [gi:6686057]
View
4
[SID103179218]
Km 10400Activity of rat liver 3-alpha-HSD assessed as formation of corresponding (S)-alcohol products [AID323691, Type: Literature]3-alpha-hydroxysteroid dehydrogenase [gi:118634]
View
5
[SID103179218]
Ratio of Vmax to Km for rat liver 3-alpha-HSD for formation of corresponding (S)-alcohol products [AID323692, Type: Literature]3-alpha-hydroxysteroid dehydrogenase [gi:118634]
View
6
[SID103179218]
Activity of rat liver 3-alpha-HSD assessed as formation of corresponding (S)-alcohol products per mg of protein [AID323693, Type: Literature]3-alpha-hydroxysteroid dehydrogenase [gi:118634]
View
7
[SID103179218]
Displacement of Y-27632 from ROCK-1 assessed as drop in intensity of binding signals by NMR competition experiment [AID551809, Type: Literature]
View
8
[SID103179218]
Aqueous solubility [AID19262, Type: Literature]
View
9
[SID103179218]
Partition coefficient (logD7.4) [AID19424, Type: Literature]
View
10
[SID103179218]
HPLC capacity factor (k) [AID19427, Type: Literature]
View
11
[SID103179218]
Partition coefficient (logP) [AID23714, Type: Literature]
View
12
[SID103179218]
Capacity ratio (log k'w) [AID23978, Type: Literature]
View
13
[SID103179218]
Partition coefficient (logP) [AID27580, Type: Literature]
View
14
[SID103179218]
Partition coefficient (logP) (dodecane) [AID28956, Type: Literature]
View
15
[SID103179218]
Partition coefficient (logP) [AID28957, Type: Literature]
View
16
[SID103179218]
Partition coefficient (logP) (HPLC) [AID29421, Type: Literature]
View
17
[SID103179218]
Binding constant against bovine serum albumin [AID203473, Type: Literature]
View
18
[SID103179218]
Toxicity determined using Tadpole Narcosis Test [AID212400, Type: Literature]
View
19
[SID103179218]
Partition coefficient (logP) [AID236904, Type: Literature]
View
20
[SID103179218]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
View
21
[SID103179218]
Octanol-water distribution coefficient, log D at pH 7.4 by shake-flask technique [AID343398, Type: Literature]
View
22
[SID103179218]
Hexadecane-water distribution coefficient, log D at pH 7.4 by shake-flask technique [AID343680, Type: Literature]
View
23
[SID103179218]
2,2,4-trimethylpentane-water partition coefficient, log P of the compound [AID343681, Type: Literature]
View
24
[SID103179218]
Hexadecane-water partition coefficient, log P of the compound [AID343682, Type: Literature]
View
25
[SID103179218]
Binding affinity to beta cyclodextrin [AID346025, Type: Literature]
View
26
[SID73468]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
View
27
[SID73468]
NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
View
28
[SID73468]
NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
View
29
[SID73468]
NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
View
30
[SID73468]
NCI Yeast Anticancer Drug Screen. Data for the bub3 strain [AID167, Type: other]
View
31
[SID73468]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
View
32
[SID144209620]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
33
[SID144209620]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
View
34
[SID144209620]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
View
35
[SID144209620]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
View
36
[SID144209620]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
View
37
[SID144209620]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
View
38
[SID144209620]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
View
39
[SID144209620]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
View
40
[SID144209620]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
View
41
[SID144209620]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
View
42
[SID144209620]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
43
[SID144209620]
Ratio Potency (uM) qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
View
44
[SID144209620]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cells [AID720674, Type: confirmatory]
View
45
[SID144209620]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cells [AID720675, Type: confirmatory]
View
46
[SID144209620]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells [AID720678, Type: confirmatory]
View
47
[SID144209620]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cells [AID720679, Type: confirmatory]
View
48
[SID144209620]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells [AID720680, Type: confirmatory]
View
49
[SID144209620]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cell free culture [AID720681, Type: confirmatory]
View
50
[SID144209620]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell free culture [AID720682, Type: confirmatory]
View