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acetophenone (CID 7410) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inactive(179)
 
 
Inconclusive(10)
 
 
Unspecified(39)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
 
NR LBD AR(14)
 
 
 
NR LBD ER(14)
 
 
NR LBD Fxr(8)
 
 
 
NR LBD VDR(8)
 
 
BioAssay Types:
Confirmatory(124)
 
 
 
Literature(53)
 
 
 
 
 
Summary(48)
 
 
 
BioActivity Types:
Potency(160)
 
 
 
IC50(12)
 
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 146    Data Row: 232   Total Pages: 12   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179218]
IC50 45.7Phytotoxicity against Lactuca sativa (lettuce) assessed as inhibition of root development during seeding stage after 120 hr [AID1101833, Type: Literature]
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2
[SID103179218]
GI50 47Phytotoxicity against Lactuca sativa (lettuce) assessed as inhibition of seed germination after 48 hr [AID1101839, Type: Literature]
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3
[SID103179218]
IC50 49.5Phytotoxicity against Lactuca sativa (lettuce) assessed as inhibition of shoot development during seeding stage after 120 hr [AID1101834, Type: Literature]
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4
[SID48415020]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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5
[SID103179218]
IC50 100Inhibition of GSK3-beta by liquid scintillation counting [AID452111, Type: Literature]
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6
[SID103179218]
IC50 125.9Phytotoxicity against Lolium multiflorum (Italian ryegrass) assessed as inhibition of shoot development during seeding stage after 120 hr [AID1101836, Type: Literature]
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7
[SID103179218]
GI50 127.5Phytotoxicity against Lolium multiflorum (Italian ryegrass) assessed as inhibition of seed germination after 48 hr [AID1101840, Type: Literature]
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8
[SID103179218]
IC50 127.9Phytotoxicity against Lolium multiflorum (Italian ryegrass) assessed as inhibition of root development during seeding stage after 120 hr [AID1101835, Type: Literature]
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9
[SID103179218]
IC50 133.5Phytotoxicity against Trifolium pratense (red clover) assessed as inhibition of root development during seeding stage after 120 hr [AID1101829, Type: Literature]
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10
[SID103179218]
IC50 137Phytotoxicity against Trifolium pratense (red clover) assessed as inhibition of shoot development during seeding stage after 120 hr [AID1101830, Type: Literature]
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11
[SID103179218]
GI50 137.3Phytotoxicity against Trifolium pratense (red clover) assessed as inhibition of seed germination after 48 hr [AID1101837, Type: Literature]
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12
[SID103179218]
IC50 850Inhibition of mushroom tyrosinase [AID327624, Type: Literature]Polyphenol oxidase 2 [gi:6686057]
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13
[SID103179218]
Km 10400Activity of rat liver 3-alpha-HSD assessed as formation of corresponding (S)-alcohol products [AID323691, Type: Literature]3-alpha-hydroxysteroid dehydrogenase [gi:118634]
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14
[SID103179218]
Ratio of Vmax to Km for rat liver 3-alpha-HSD for formation of corresponding (S)-alcohol products [AID323692, Type: Literature]3-alpha-hydroxysteroid dehydrogenase [gi:118634]
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15
[SID103179218]
Activity of rat liver 3-alpha-HSD assessed as formation of corresponding (S)-alcohol products per mg of protein [AID323693, Type: Literature]3-alpha-hydroxysteroid dehydrogenase [gi:118634]
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16
[SID103179218]
Nematicidal activity against Bursaphelenchus xylophilus assessed as nematode mortality at 2 mg/mL measured 24 hr post dose by microscopy [AID1080381, Type: Literature]
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17
[SID103179218]
Phytotoxicity against Lactuca sativa (lettuce) assessed as inhibition of seed germination at 500 uM after 48 hr [AID1101821, Type: Literature]
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18
[SID103179218]
Phytotoxicity against Lolium multiflorum (Italian ryegrass) assessed as inhibition of seed germination at 500 uM after 48 hr [AID1101822, Type: Literature]
View
19
[SID103179218]
Inverse agonist activity at human RORgamma expressed in HEK293 cells at 10 uM after 18 hrs by luciferase reporter gene assay [AID1072617, Type: Literature]Nuclear receptor ROR-gamma [gi:49066040]
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20
[SID103179218]
Inverse agonist activity at human RORgamma expressed in HEK293 cells at 1 uM after 18 hrs by luciferase reporter gene assay [AID1072618, Type: Literature]Nuclear receptor ROR-gamma [gi:49066040]
View