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tetramethylthiuram monosulfide (CID 7347) - Compound BioActivity Data
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BioActivity Outcomes:
Active(134)
 
 
Inactive(166)
 
 
Inconclusive(146)
 
 
Unspecified(4)
 
 
Top Targets:
NR LBD PPAR(29)
 
 
 
 
NR LBD ER(23)
 
 
 
 
NR LBD AR(23)
 
 
 
 
NR LBD VDR(15)
 
 
 
 
NR LBD TR(15)
 
 
 
 
BioAssay Types:
Confirmatory(280)
 
 
 
 
Summary(72)
 
 
 
 
Literature(65)
 
 
 
 
 
Screening(7)
 
 
BioActivity Types:
Potency(330)
 
 
 
 
IC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 196    Data Row: 450   Total Pages: 23   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213197]
Potency-Replicate_1 0.0969qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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2
[SID144213197]
Potency-Replicate_1 0.0969qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
3
[SID144213197]
Ratio Potency (uM) 0.143405qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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4
[SID144213197]
Potency-Replicate_1 0.1723qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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5
[SID144213197]
Potency-Replicate_1 0.2434qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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6
[SID144213197]
Potency-Replicate_1 0.2434qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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7
[SID144213197]
Potency-Replicate_1 0.3064qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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8
[SID144208752]
Potency-Replicate_1 0.317qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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9
[SID144213197]
Potency-Replicate_1 0.3467qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
10
[SID144213197]
Potency-Replicate_1 0.389qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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11
[SID144213197]
Potency-Replicate_1 0.4328qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
View
12
[SID144213197]
Potency-Replicate_1 0.4856qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
View
13
[SID144208752]
Potency-Replicate_1 0.5024qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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14
[SID144213197]
Potency-Replicate_1 0.5494qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
View
15
[SID144208752]
Potency-Replicate_1 0.5637qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
View
16
[SID170465567]
Potency-Replicate_1 0.5955qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743215, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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17
[SID144208752]
Ratio Potency (uM) 0.60866qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
View
18
[SID144213197]
Potency-Replicate_1 0.6917qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
View
19
[SID144208752]
Potency-Replicate_1 0.7096qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
View
20
[SID144205209]
Potency-Replicate_1 0.7498qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View