4-Butyrolactone (CID 7302) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Inactive(14)
 
 
Unspecified(2)
 
 
Top Targets:
Str synth(1)
 
 
BioAssay Types:
Literature(3)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 16    Data Row: 16   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103310643]
 Second-order rate constant (M-1 s-1) for the alkaline hydrolysis in water at 30 degrees C [AID28486, Type: Literature]
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2
[SID103310643]
 Activity at human recombinant PON1 assessed as hydrolysis of lactone ring at 1 mM by Ellman's method [AID342465, Type: Literature]Serum paraoxonase/arylesterase 1 [gi:308153572]
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3
[SID103310643]
 Binding affinity towards [3H]GHB binding site at 10 uM [AID71720, Type: Literature]Gamma-hydroxybutyrate receptor [gi:81870762]
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4
[SID70860]
 NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
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5
[SID70860]
 NCI Yeast Anticancer Drug Screen. Data for the bub3 strain [AID167, Type: other]
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6
[SID70860]
 NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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7
[SID70860]
 NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID248, Type: other]
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8
[SID70860]
 NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
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9
[SID48413356]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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10
[SID48413356]
 DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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11
[SID48413356]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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12
[SID48413356]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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13
[SID48413356]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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14
[SID70860]
 NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
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15
[SID70860]
 NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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16
[SID70860]
 NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID256, Type: other]
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