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alkannin (CID 72521) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(14)
 
 
Inactive(2)
 
 
Unspecified(27)
 
 
BioAssay Types:
Literature(43)
 
 
 
 
BioActivity Types:
IC50(14)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 43    Data Row: 43   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103200891]
IC50 0.7Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay [AID481862, Type: Literature]
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2
[SID103200891]
IC50 0.78Cytotoxicity against human SKBR3 cells after 48 hrs by MTT assay [AID481858, Type: Literature]
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3
[SID103200891]
IC50 0.9Cytotoxicity against human AU565 cells after 48 hrs by MTT assay [AID481853, Type: Literature]
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4
[SID103200891]
IC50 0.91Cytotoxicity against human HeLa cells after 48 hrs by MTT assay [AID481857, Type: Literature]
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5
[SID103200891]
IC50 2.31Cytotoxicity against human Saos2 cells after 48 hrs by MTT assay [AID481860, Type: Literature]
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6
[SID103200891]
IC50 3.06Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay [AID481856, Type: Literature]
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7
[SID103200891]
IC50 3.25Cytotoxicity against human PC3 cells after 48 hrs by MTT assay [AID481852, Type: Literature]
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8
[SID103200891]
IC50 3.8Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay [AID481854, Type: Literature]
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9
[SID103200891]
IC50 3.84Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay [AID481861, Type: Literature]
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10
[SID103200891]
IC50 4.03Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay [AID481850, Type: Literature]
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11
[SID103200891]
IC50 4.27Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay [AID481851, Type: Literature]
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12
[SID103200891]
IC50 5.02Cytotoxicity against human DU145 cells after 48 hrs by MTT assay [AID481859, Type: Literature]
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13
[SID103200891]
IC50 5.21Cytotoxicity against mouse 3T3 cells after 48 hrs by MTT assay [AID481863, Type: Literature]
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14
[SID103200891]
IC50 10.74Cytotoxicity against human LNCAP cells after 48 hrs by MTT assay [AID481855, Type: Literature]
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15
[SID103200891]
MIC 500Inhibition of topoisomerase I [AID228426, Type: Literature]
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16
[SID103200891]
Decrease in histamine-induced capillary permeability in Wistar rat assessed as inhibition of pontamine sky blue 6BX dye leakage at 50 ug treated topically relative to control [AID332845, Type: Literature]
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17
[SID103200891]
Decrease in histamine-induced capillary permeability in Wistar rat assessed as inhibition of pontamine sky blue 6BX dye leakage at 100 ug treated topically relative to control [AID332846, Type: Literature]
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18
[SID103200891]
Binding affinity to human telomeric G-quadruplex DNA at 200 uM after 1 hr by ESI-TOF-MS analysis [AID646469, Type: Literature]
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19
[SID103200891]
The compound was tested in vitro for its cytotoxicity against human A-549 cancer cell line by MTT method at 1 uM concentration; Slight inhibition [AID8453, Type: Literature]
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20
[SID103200891]
The compound was tested in vitro for its cytotoxicity against human HL-60 cancer cell line by MTT method at 1 uM concentration; Slight inhibition [AID81147, Type: Literature]
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21
[SID103200891]
The compound was tested in vitro for its cytotoxicity against human P-388 cancer cell line by MTT method at 1 uM concentration; Slight inhibition [AID152352, Type: Literature]
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22
[SID103200891]
Ratio of MBC to MIC for Staphylococcus aureus [AID357213, Type: Literature]
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23
[SID103200891]
Ratio of MBC to MIC for methicillin-resistant Staphylococcus aureus 8-8S [AID357214, Type: Literature]
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24
[SID103200891]
Ratio of MBC to MIC for Enterococcus faecalis [AID357215, Type: Literature]
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25
[SID103200891]
Ratio of MBC to MIC for vancomycin-resistant Enterococcus faecium F935 expressing VanA [AID357216, Type: Literature]
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26
[SID103200891]
Antibacterial activity against Enterococcus faecalis after 24 hrs by broth microdilution method [AID356962, Type: Literature]
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27
[SID103200891]
Antibacterial activity against Enterococcus faecalis after 48 hrs by broth microdilution method [AID356963, Type: Literature]
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28
[SID103200891]
Antibacterial activity against vancomycin-resistant Enterococcus faecium F935 expressing VanA after 24 hrs by broth microdilution method [AID356964, Type: Literature]
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29
[SID103200891]
Antibacterial activity against vancomycin-resistant Enterococcus faecium F935 expressing VanA after 48 hrs by broth microdilution method [AID356965, Type: Literature]
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30
[SID103200891]
Antibacterial activity against vancomycin-resistant Enterococcus faecalis CKU-17 expressing VanB after 24 hrs by broth microdilution method [AID356966, Type: Literature]
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31
[SID103200891]
Antibacterial activity against vancomycin-resistant Enterococcus faecalis CKU-17 expressing VanB after 48 hrs by broth microdilution method [AID356967, Type: Literature]
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32
[SID103200891]
Antiinflammatory activity against thermal injury-induced edema in Wistar rat skin assessed as inhibition of edema at 50 ug treated topically relative to control [AID332847, Type: Literature]
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33
[SID103200891]
Antiinflammatory activity against thermal injury-induced edema in Wistar rat skin assessed as inhibition of edema at 100 ug treated topically relative to control [AID332848, Type: Literature]
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34
[SID103200891]
Antibacterial activity against Staphylococcus aureus after 24 hrs by broth microdilution method [AID356958, Type: Literature]
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35
[SID103200891]
Antibacterial activity against Staphylococcus aureus after 48 hrs by broth microdilution method [AID356959, Type: Literature]
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36
[SID103200891]
Antibacterial activity against methicillin-resistant Staphylococcus aureus 8-8S after 24 hrs by broth microdilution method [AID356960, Type: Literature]
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37
[SID103200891]
Antibacterial activity against methicillin-resistant Staphylococcus aureus 8-8S after 48 hrs by broth microdilution method [AID356961, Type: Literature]
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38
[SID103200891]
Ratio of MBC to MIC for vancomycin-resistant Enterococcus faecalis CKU-17 expressing VanB [AID357217, Type: Literature]
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39
[SID103200891]
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay [AID357226, Type: Literature]
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40
[SID103200891]
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay [AID357227, Type: Literature]
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41
[SID103200891]
Cytotoxicity against human OVCAR-3 cells after 48 hrs by MTT assay [AID357228, Type: Literature]
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42
[SID103200891]
Antibacterial activity against Escherichia coli up to 100 ug/mL after 24 hrs by broth microdilution method [AID356968, Type: Literature]
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43
[SID103200891]
Antibacterial activity against Pseudomonas aeruginosa up to 100 ug/mL after 24 hrs by broth microdilution method [AID357212, Type: Literature]
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