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Nonoxynol (CID 72385) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(100)
 
 
Inconclusive(43)
 
 
Unspecified(45)
 
 
Top Targets:
Bromo ALL-1(3)
 
 
 
HSD10-like SD..(2)
 
 
DUF3652(2)
 
 
globin(2)
 
 
NR LBD TR(2)
 
 
BioAssay Types:
Literature(113)
 
 
 
 
 
Confirmatory(77)
 
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(74)
 
 
 
 
IC50(5)
 
 
 
Ki(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 133    Data Row: 199   Total Pages: 10   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103486474]
Ki 1.92Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells [AID977601, Type: Literature]
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2
[SID103486474]
IC50 2.31HARVARD: Inhibition of liver stage Plasmodium berghei infection in HepG2 cells [AID685501, Type: Literature]
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3
[SID103486474]
Ki 2.87Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells [AID977604, Type: Literature]
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4
[SID103486474]
IC50 3.46737pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells [AID977600, Type: Literature]
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5
[SID103486474]
IC50 3.71535pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells [AID977603, Type: Literature]
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6
[SID26749924]
Potency 8.4921Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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7
[SID26749924]
Potency 31.6228qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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8
[SID26749924]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_56, Type: Literature]
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9
[SID92308132]
A screen for compounds that inhibit liver stage malaria [AID624349, Type: other]
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10
[SID26749924]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_3, Type: Literature]
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11
[SID26749924]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_19, Type: Literature]
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12
[SID103486474]
IC50 5HARVARD: Inhibition of blood stage Plasmodium falciparum Dd2 infection [AID685503, Type: Literature]
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13
[SID103486474]
IC50 61HARVARD: Cytotoxicity in HepG2 cell line [AID685500, Type: Literature]
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14
[SID103486474]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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15
[SID103486474]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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16
[SID103486474]
Sperimcidal activity against human spermatozoa assessed as sperm motility at 1 % drug solution% [AID467900, Type: Literature]
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17
[SID103486474]
Antitrichomonal activity against Trichomonas vaginalis after 48 hrs by trypan blue exclusion assay [AID467902, Type: Literature]
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18
[SID103486474]
Antifungal activity against Candida albicans after 48 hrs by broth microdilution technique [AID467903, Type: Literature]
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19
[SID103486474]
Antifungal activity against Candida parapsilosis after 48 hrs by broth microdilution technique [AID467908, Type: Literature]
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20
[SID103486474]
Cytotoxicity against human HeLa cells at 200 ug/ml after 24 hrs by MTT assay [AID467909, Type: Literature]
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