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Nonoxynol (CID 72385) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(100)
 
 
Inconclusive(43)
 
 
Unspecified(43)
 
 
Top Targets:
Bromo ALL-1(3)
 
 
 
HSD10-like SD..(2)
 
 
DUF3652(2)
 
 
globin(2)
 
 
NR LBD TR(2)
 
 
BioAssay Types:
Literature(104)
 
 
 
 
 
Confirmatory(77)
 
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(74)
 
 
 
 
IC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 127    Data Row: 193   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103486474]
IC50 2.31HARVARD: Inhibition of liver stage Plasmodium berghei infection in HepG2 cells [AID685501, Type: other]
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2
[SID26749924]
Potency 8.4921Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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3
[SID26749924]
Potency 31.6228qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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4
[SID92308132]
A screen for compounds that inhibit liver stage malaria [AID624349, Type: other]
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5
[SID26749924]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_56, Type: Literature]
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6
[SID26749924]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_19, Type: Literature]
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7
[SID26749924]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_3, Type: Literature]
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8
[SID103486474]
IC50 5HARVARD: Inhibition of blood stage Plasmodium falciparum Dd2 infection [AID685503, Type: other]
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9
[SID103486474]
MIC 60.78Antitrichomonal activity against Trichomonas vaginalis after 48 hrs by trypan blue exclusion assay [AID467902, Type: Literature]
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10
[SID103486474]
IC50 61HARVARD: Cytotoxicity in HepG2 cell line [AID685500, Type: other]
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11
[SID103486474]
Sperimcidal activity against human spermatozoa assessed as sperm motility at 1 % drug solution% [AID467900, Type: Literature]
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12
[SID103486474]
Spermicidal activity against human spermatozoa [AID263884, Type: Literature]
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13
[SID103486474]
Cytotoxicity against human HeLa cells by MTT assay [AID677472, Type: Literature]
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14
[SID103486474]
Antimicrobial activity against Lactobacillus jensenii [AID677473, Type: Literature]
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15
[SID103486474]
Antifungal activity against Candida albicans after 48 hrs by broth microdilution technique [AID467903, Type: Literature]
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16
[SID103486474]
Antifungal activity against Candida parapsilosis after 48 hrs by broth microdilution technique [AID467908, Type: Literature]
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17
[SID103486474]
Spermicidal activity against human spermatozoa assessed as immobilization measured for 60 seconds [AID664682, Type: other]
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18
[SID103486474]
Cytotoxicity against human HeLa cells [AID664683, Type: other]
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19
[SID103486474]
Toxicity against Lactobacillus jensenii ATCC 25258 [AID664684, Type: other]
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20
[SID103486474]
Spermicidal activity against human spermatozoa at 10 mg/ml by modified sander-cramer assay [AID677410, Type: Literature]
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21
[SID103486474]
Antimicrobial activity against clinical isolate of Trichomonas vaginalis [AID677470, Type: Literature]
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22
[SID103486474]
Antimicrobial activity against Trichomonas vaginalis ATCC 25258 [AID677471, Type: Literature]
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23
[SID103486474]
Antifungal activity against Candida parapsilosis after 48 hrs by broth microdilution assay [AID550087, Type: Literature]
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24
[SID103486474]
Antifungal activity against Candida albicans MTCC-183 after 48 hrs by broth microdilution assay [AID550088, Type: Literature]
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25
[SID103486474]
Antifungal activity against Candida albicans isolate CDRI after 48 hrs by broth microdilution assay [AID550089, Type: Literature]
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26
[SID103486474]
Antifungal activity against Candida albicans NCIM-3557 after 48 hrs by broth microdilution assay [AID550090, Type: Literature]
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27
[SID103486474]
Toxicity against human cervical tissue explants after 2 hrs by MTT assay [AID571948, Type: Literature]
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28
[SID103486474]
Toxicity against human cervical tissue explants after 24 hrs by MTT assay [AID571949, Type: Literature]
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29
[SID103486474]
Cytotoxicity against human HeLa cells at 200 ug/ml after 24 hrs by MTT assay [AID467909, Type: Literature]
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30
[SID103486474]
Toxicity against Lactobacillus acidophilus at 200 ug/ml after 24 hrs by microplate reader [AID550082, Type: Literature]
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31
[SID103486474]
Cytotoxicity against human HeLa cells at 200 ug/ml after 24 hrs by MTT based colorimetric assay [AID550083, Type: Literature]
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32
[SID103486474]
Spermicidal activity against human spermatozoa assessed as immobilization measured for 60 seconds by visual scoring [AID550084, Type: Literature]
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33
[SID103486474]
Antitrichomonas activity against Trichomonas vaginalis after 48 hrs by trypan blue exclusion assay [AID550085, Type: Literature]
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34
[SID103486474]
Antifungal activity against Candida albicans after 48 hrs by broth microdilution assay [AID550086, Type: Literature]
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35
[SID103486474]
Antifungal activity against Candida parapsilosis ATCC 22019 after 48 hrs by broth microdilution technique [AID386926, Type: Literature]
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36
[SID103486474]
Antifungal activity against Candida krusei ATCC 6258 after 48 hrs by broth micro dilution technique [AID301288, Type: Literature]
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37
[SID103486474]
Antifungal activity against Candida parapsilosis ATCC 22019 after 48 hrs by broth micro dilution technique [AID301289, Type: Literature]
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38
[SID103486474]
Antifungal activity against Candida albicans ATCC 10453 after 48 hrs by broth micro dilution technique [AID301290, Type: Literature]
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39
[SID103486474]
Antifungal activity against Candida albicans ATCC 60193 after 48 hrs by broth micro dilution technique [AID301291, Type: Literature]
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40
[SID103486474]
Antifungal activity against Candida albicans ATCC 66027 after 48 hrs by broth micro dilution technique [AID301292, Type: Literature]
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41
[SID103486474]
Spermicidal activity in liquefied human semen assessed as drug level required to kill 100% sperm in 20 seconds [AID386920, Type: Literature]
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42
[SID103486474]
Antitrichomonas activity against Trichomonas vaginalis after 48 hrs [AID263885, Type: Literature]
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43
[SID103486474]
Spermicidal activity against human spermatozoa [AID301282, Type: Literature]
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44
[SID103486474]
Antifungal activity against Candida albicans after 48 hrs by broth micro dilution technique [AID301284, Type: Literature]
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45
[SID103486474]
Antifungal activity against Candida albicans MTCC 183 after 48 hrs by broth micro dilution technique [AID301285, Type: Literature]
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46
[SID103486474]
Antifungal activity against Candida albicans MTCC 1346 after 48 hrs by broth micro dilution technique [AID301286, Type: Literature]
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47
[SID103486474]
Antifungal activity against Candida albicans ATCC 10231 after 48 hrs by broth micro dilution technique [AID301287, Type: Literature]
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48
[SID103486474]
Antitrichomonas activity against Trichomonas vaginalis after 48 hrs by trypan blue staining [AID386927, Type: Literature]
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49
[SID103486474]
Spermicidal activity in rat spermatozoa assessed as sperm mobilization [AID433251, Type: Literature]
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50
[SID26749924]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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