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BioActivity Data for Compound indene (CID 7219)

BioActivity Outcomes:
Active(2)
 
 
Inactive(96)
 
 
Inconclusive(5)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
 
NR LBD Fxr(4)
 
 
NR LBD GR(4)
 
 
 
BioAssay Types:
Confirmatory(72)
 
 
 
 
Summary(28)
 
 
 
 
Literature(5)
 
 
 
BioAssay Categories:
In vitro(3)
 
 
Biochemical(5)
 
 
 
Toxicity(6)
 
 
Cell-based(3)
 
 
BioActivity Types:
Potency(94)
 
 
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 105    Data Row: 105   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144211532]
AhR Potency (uM) 13.6854qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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2
[SID144211532]
Potency-Replicate_1 27.306qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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3
[SID103463831]
Kd 193Dissociation constant against T4 lysozyme mutant L99A [AID238119, Type: Literature]Endolysin [gi:635377407]
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4
[SID103463831]
Inhibition of chymotrypsin (unknown origin) [AID1149945, Type: Literature]
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5
[SID144211532]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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6
[SID144211532]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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7
[SID144211532]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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8
[SID144211532]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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9
[SID144211532]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the NFkB signaling pathway - cell viability counter screen [AID1159515, Type: confirmatory]
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10
[SID144211532]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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11
[SID144211532]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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12
[SID144211532]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the AP-1 signaling pathway - cell viability counter screen [AID1159525, Type: confirmatory]
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13
[SID144211532]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the AP-1 signaling pathway [AID1159526, Type: confirmatory]
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14
[SID103463831]
Inhibition of rabbit liver carboxylesterase expressed in sf21 cells up to 100 uM [AID281484, Type: Literature]
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15
[SID103463831]
Inhibition of human intestinal carboxylesterase expressed in sf21 cells up to 100 uM [AID281482, Type: Literature]
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16
[SID144211532]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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17
[SID144211532]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cells [AID720687, Type: confirmatory]
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18
[SID144211532]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cell free culture [AID720685, Type: confirmatory]
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19
[SID144211532]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cell free culture [AID720684, Type: confirmatory]
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20
[SID144211532]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cell free culture [AID720683, Type: confirmatory]
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