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BioActivity Data for Compound fluphenacur (CID 71777)

BioActivity Outcomes:
Active(31)
 
 
Inactive(342)
 
 
Inconclusive(76)
 
 
Unspecified(163)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD ER(16)
 
 
 
NR LBD AR(16)
 
 
 
 
NR LBD VDR(12)
 
 
 
NR LBD TR(12)
 
 
BioAssay Types:
Confirmatory(281)
 
 
 
 
Literature(243)
 
 
 
 
 
Summary(54)
 
 
 
 
Screening(24)
 
 
BioAssay Categories:
In vitro(2)
 
 
Biochemical(4)
 
 
Toxicity(24)
 
 
 
 
 
ADME(3)
 
 
Cell-based(17)
 
 
 
BioActivity Types:
Potency(313)
 
 
 
 
AC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 420    Data Row: 612   Total Pages: 31   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144205095]
Potency-Replicate_1 3.3491qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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2
[SID144205095]
Potency-Replicate_1 4.2163qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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3
[SID144205095]
Potency-Replicate_1 5.308qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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4
[SID144205095]
Potency-Replicate_1 5.9557qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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5
[SID144205095]
Ratio Potency (uM) 6.04487qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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6
[SID144205095]
Potency-Replicate_1 6.6824qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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7
[SID144211224]
Potency-Replicate_1 7.6959qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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8
[SID144211224]
Potency-Replicate_1 7.6959qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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9
[SID26749995]
Potency 15.8489qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase, partial [Homo sapiens] [gi:1832253]
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10
[SID170465736]
AC50 (uM) 17.7828qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue channel [AID1117304, Type: confirmatory]
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11
[SID144205095]
Potency 19.3312qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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12
[SID170465736]
AC50 (uM) 19.9526qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio channel [AID1117305, Type: confirmatory]
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13
[SID170465736]
Ac50 19.9526qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
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14
[SID144211224]
Potency-Replicate_1 21.6899qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
15
[SID144211224]
AR Potency (uM) 22.9752qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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16
[SID160677172]
Effect on fecundity in 7 days old adult of Anastrepha striata at 0.1 to 30 mg/g treated with diet after 24 hr [AID1111570, Type: Literature]
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17
[SID160677172]
Effect on fecundity in 7 days old adult of Anastrepha serpentina at 0.1 to 30 mg/g treated with diet after 24 hr [AID1111571, Type: Literature]
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18
[SID144205095]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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19
[SID144205095]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
View
20
[SID144205095]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
View