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fluphenacur (CID 71777) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(28)
 
 
Inactive(282)
 
 
Inconclusive(81)
 
 
Unspecified(17)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD ER(16)
 
 
 
NR LBD AR(16)
 
 
 
 
NR LBD TR(12)
 
 
NR LBD VDR(12)
 
 
 
BioAssay Types:
Confirmatory(257)
 
 
 
 
Literature(77)
 
 
 
 
 
Summary(48)
 
 
 
 
Screening(16)
 
 
BioActivity Types:
Potency(289)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 227    Data Row: 408   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144205095]
Potency-Replicate_1 3.3491qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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2
[SID144205095]
Potency-Replicate_1 4.2163qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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3
[SID144205095]
Potency-Replicate_1 5.308qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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4
[SID144205095]
Potency-Replicate_1 5.9557qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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5
[SID144205095]
Ratio Potency (uM) 6.04487qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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6
[SID144205095]
Potency-Replicate_1 6.6824qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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7
[SID144211224]
Potency-Replicate_1 7.6959qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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8
[SID144211224]
Potency-Replicate_1 7.6959qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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9
[SID144211224]
Potency-Replicate_1 7.6959qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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10
[SID144211224]
Potency-Replicate_1 8.6349qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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11
[SID144211224]
Potency-Replicate_1 10.8707qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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12
[SID26749995]
Potency 15.8489qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase [Homo sapiens] [gi:1832253]
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13
[SID144205095]
Potency 19.3312qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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14
[SID144211224]
AR Potency (uM) 22.9752qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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15
[SID144205095]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
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16
[SID144205095]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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17
[SID144205095]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_8, Type: other]
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18
[SID144205095]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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19
[SID144205095]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
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20
[SID144205095]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
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21
[SID144205095]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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22
[SID26753780]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_58, Type: Literature]
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23
[SID26753780]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_39, Type: Literature]
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24
[SID26753780]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_43, Type: Literature]
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25
[SID26753780]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_29, Type: Literature]
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26
[SID26753780]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_13, Type: Literature]
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27
[SID26753780]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_7, Type: Literature]
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28
[SID26753780]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_4, Type: Literature]
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29
[SID26753780]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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30
[SID144205095]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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31
[SID160677172]
Antifungal activity against Candida albicans after 48 hrs by microbroth dilution method [AID677610, Type: Literature]
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32
[SID160677172]
Antifungal activity against Candida albicans NCIM 3471 after 48 hrs by microbroth dilution method [AID677611, Type: Literature]
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33
[SID160677172]
Antifungal activity against Candida glabrata NCIM 3237 after 48 hrs by microbroth dilution method [AID677612, Type: Literature]
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34
[SID160677172]
Antifungal activity against Cryptococcus neoformans after 48 hrs by microbroth dilution method [AID677613, Type: Literature]
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35
[SID160677172]
Antifungal activity against Cryptococcus neoformans NCIM 3541 after 48 hrs by microbroth dilution method [AID677614, Type: Literature]
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36
[SID160677172]
Antifungal activity against Cryptococcus neoformans NCIM 3542 after 48 hrs by microbroth dilution method [AID677615, Type: Literature]
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37
[SID160677172]
Antifungal activity against Magnaporthe grisea after 48 hrs by microbroth dilution method [AID677534, Type: Literature]
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38
[SID160677172]
Antifungal activity against Fusarium oxysporum after 48 hrs by microbroth dilution method [AID677535, Type: Literature]
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39
[SID160677172]
Antifungal activity against Dreschlera oryzae after 48 hrs by microbroth dilution method [AID677536, Type: Literature]
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40
[SID160677172]
Antifungal activity against Debaryomyces hansenii after 48 hrs by microbroth dilution method [AID677537, Type: Literature]
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41
[SID160677172]
Antifungal activity against Pichia membranifaciens after 48 hrs by microbroth dilution method [AID677538, Type: Literature]
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42
[SID160677172]
Antifungal activity against Candida albicans NCIM 3557 after 48 hrs by microbroth dilution method [AID677539, Type: Literature]
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43
[SID160677172]
Insecticidal activity against 5th instar nymph of Dysdercus koenigii assessed as mortality per nymph [AID677530, Type: Literature]
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44
[SID160677172]
Antifungal activity against Cryptococcus neoformans NCIM 3378 after 48 hrs by microbroth dilution method [AID677616, Type: Literature]
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45
[SID160677172]
Toxicity in RBC assessed as induction of hemolysis [AID677617, Type: Literature]
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46
[SID144211224]
Potency-Replicate_1 3.8895qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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47
[SID144205095]
Potency-Replicate_1 5.3538qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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48
[SID26749995]
Potency 12.5893qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID927, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
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49
[SID26753780]
Potency 17.7828qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
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50
[SID26753780]
Potency 17.7828qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens] [gi:56550039]
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