Bookmark and Share
4'-N-benzoylstaurosporine (CID 71719722) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(628)
 
 
Unspecified(1073)
 
 
Top Targets:
PKc(135)
 
 
 
PKc like(110)
 
 
 
STKc AGC(58)
 
 
 
PTKc Abl(28)
 
 
 
CYCLIN(24)
 
 
BioAssay Types:
Literature(1183)
 
 
 
BioActivity Types:
Kd(1164)
 
 
 
IC50(7)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1651    Data Row: 1701   Total Pages: 35   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID164144585]
Kd 0.002Binding affinity to FLT3 K663Q mutant [AID507956, Type: Literature]
View
2
[SID164144585]
Kd 0.002Binding constant for FLT3(K663Q) kinase domain [AID624938, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
3
[SID164144585]
Kd 0.006Binding constant for FLT3(N841I) kinase domain [AID624939, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
4
[SID164144585]
Kd 0.006Binding affinity to FLT3 N841I mutant [AID507957, Type: Literature]
View
5
[SID164144585]
Kd 0.006Binding constant for FLT3(N841I) kinase domain [AID435162, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
6
[SID164144585]
Kd 0.0068Binding constant for FLT3(D835H) kinase domain [AID435406, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
7
[SID164144585]
Kd 0.0068Binding affinity to FLT3 D835H mutant [AID507953, Type: Literature]
View
8
[SID164144585]
Kd 0.0068Binding constant for FLT3(D835H) kinase domain [AID624935, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
9
[SID164144585]
Kd 0.0077Binding affinity to human KIT D816V mutant incubated for 1 hr by kinase binding assay [AID599959, Type: Literature]
View
10
[SID164144585]
Kd 0.0077Binding constant for KIT(D816V) kinase domain [AID624789, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
11
[SID164144585]
Kd 0.0077Binding affinity to KIT D816V mutant [AID507580, Type: Literature]
View
12
[SID164144585]
Kd 0.0077Binding constant for KIT(D816V) kinase domain [AID435411, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
13
[SID164144585]
Kd 0.0088Binding constant for EGFR(L858R,T790M) kinase domain [AID625004, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
14
[SID164144585]
Kd 0.0093Binding constant for TBK1 kinase domain [AID625072, Type: Literature]Serine/threonine-protein kinase TBK1 [gi:74761953]
View
15
[SID164144585]
Kd 0.0093Binding constant for PKN1 kinase domain [AID624745, Type: Literature]Serine/threonine-protein kinase N1 [gi:259016304]
View
16
[SID164144585]
Kd 0.0093Binding affinity to TBK1 [AID508104, Type: Literature]
View
17
[SID164144585]
Kd 0.0093Binding affinity to PKN1 [AID508037, Type: Literature]
View
18
[SID164144585]
Kd 0.0093Binding constant for PKN1 kinase domain [AID435319, Type: Literature]Serine/threonine-protein kinase N1 [gi:259016304]
View
19
[SID164144585]
Kd 0.0098Binding constant for EGFR(T790M) kinase domain [AID625007, Type: Literature]Epidermal growth factor receptor [gi:2811086]
View
20
[SID164144585]
Kd 0.011Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
21
[SID164144585]
Kd 0.011Binding constant for FLT3 kinase domain [AID624934, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
22
[SID164144585]
Kd 0.011Binding constant for FLT3(ITD) kinase domain [AID435310, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
23
[SID164144585]
Kd 0.011Binding constant for FLT3 kinase domain [AID435799, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
24
[SID164144585]
Kd 0.011Binding affinity to FLT3 [AID507952, Type: Literature]
View
25
[SID164144585]
Kd 0.011Binding affinity to FLT3 ITD mutant [AID507955, Type: Literature]
View
26
[SID164144585]
Kd 0.011Binding affinity to FLT3 catalytic domain by KinomeScan kinase binding assay [AID507803, Type: Literature]
View
27
[SID164144585]
IC50 0.012Cytotoxicity against human MV4-11 cells after 72 hrs by cell titer-blue assay [AID507806, Type: Literature]
View
28
[SID164144585]
Kd 0.012Binding affinity to JH1 catalytic domain of JAK3 [AID507575, Type: Literature]
View
29
[SID164144585]
Kd 0.012Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domain [AID435674, Type: Literature]Tyrosine-protein kinase JAK3 [gi:50403745]
View
30
[SID164144585]
Kd 0.012Binding constant for FLT3(R834Q) kinase domain [AID624940, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
31
[SID164144585]
Kd 0.012Binding constant for JAK3(JH1domain-catalytic) kinase domain [AID624785, Type: Literature]Tyrosine-protein kinase JAK3 [gi:50403745]
View
32
[SID164144585]
IC50 0.013Inhibition of FLT3 ITD mutant autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assay [AID507804, Type: Literature]
View
33
[SID164144585]
IC50 0.015Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assay [AID507805, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
34
[SID164144585]
Kd 0.015Binding affinity to FLT3 D835Y mutant [AID507954, Type: Literature]
View
35
[SID164144585]
Kd 0.015Binding affinity to MLK1 [AID507626, Type: Literature]
View
36
[SID164144585]
Kd 0.015Binding constant for PKN2 kinase domain [AID435933, Type: Literature]Serine/threonine-protein kinase N2 [gi:6225859]
View
37
[SID164144585]
Kd 0.015Binding constant for MLK1 kinase domain [AID435297, Type: Literature]Mitogen-activated protein kinase kinase kinase 9 [gi:116242625]
View
38
[SID164144585]
Kd 0.015Binding constant for FLT3(D835Y) kinase domain [AID435407, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
39
[SID164144585]
Kd 0.015Binding affinity to PKN2 [AID508038, Type: Literature]
View
40
[SID164144585]
Kd 0.015Binding constant for MLK1 kinase domain [AID624706, Type: Literature]Mitogen-activated protein kinase kinase kinase 9 [gi:116242625]
View
41
[SID164144585]
Kd 0.015Binding affinity to YSK4 [AID508136, Type: Literature]
View
42
[SID164144585]
Kd 0.015Binding constant for FLT3(D835Y) kinase domain [AID624936, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
43
[SID164144585]
Kd 0.015Binding constant for PKN2 kinase domain [AID625050, Type: Literature]Serine/threonine-protein kinase N2 [gi:6225859]
View
44
[SID164144585]
Kd 0.015Binding constant for YSK4 kinase domain [AID625136, Type: Literature]Mitogen-activated protein kinase kinase kinase 19 [gi:74755104]
View
45
[SID164144585]
Kd 0.016Binding constant for KIT(D816H) kinase domain [AID624788, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
46
[SID164144585]
Kd 0.017Binding constant for MLK3 kinase domain [AID624866, Type: Literature]Mitogen-activated protein kinase kinase kinase 11 [gi:71153819]
View
47
[SID164144585]
Kd 0.017Binding constant for MLK3 kinase domain [AID435414, Type: Literature]Mitogen-activated protein kinase kinase kinase 11 [gi:71153819]
View
48
[SID164144585]
Kd 0.017Binding affinity to MST1 [AID507631, Type: Literature]
View
49
[SID164144585]
Kd 0.02Binding affinity to CAMK2A [AID507855, Type: Literature]
View
50
[SID164144585]
Kd 0.02Binding constant for CAMK2A kinase domain [AID435520, Type: Literature]Calcium/calmodulin-dependent protein kinase type II subunit alpha [gi:296434552]
View