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CHEMBL2347393 (CID 71305074) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Top Targets:
SWIB(1)
 
 
BioAssay Types:
Literature(3)
 
 
BioActivity Types:
IC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2    Data Row: 3   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID164141338]
IC50 0.61Inhibition of human recombinant GST-thrombin-MDM2 (1 to 188) expressed in Escherichia coli assessed as reduction of MDM2-p53 interaction incubated for 20 mins followed by p53 addition measured after 60 mins by HTRF assay [AID739073, Type: Literature]E3 ubiquitin-protein ligase Mdm2 [gi:266516]
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2
[SID208012899]
IC50 0.61Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]
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3
[SID208012899]
IC50 0.61Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]
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