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ML226 (CID 71304779) - Compound BioActivity Data
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BioActivity Outcomes:
Probe(1)
 
 
Active(10)
 
 
Inactive(22)
 
 
Unspecified(9)
 
 
Top Targets:
Esterase lipa..(12)
 
 
 
Abhydrolase 2(6)
 
 
 
 
PLN02442(2)
 
 
Lipase 3(1)
 
 
PAF-AH p II(1)
 
 
BioAssay Types:
Confirmatory(12)
 
 
 
Summary(10)
 
 
 
BioActivity Types:
IC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 14    Data Row: 42   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID99445332]
Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202, Type: summary]acyl-protein thioesterase 1 isoform 1 [Homo sapiens] [gi:5453722]
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2
[SID99445332]
IC50 0.000678Late stage assay provider results from the probe development effort to identify inhibitors of LYPLA1: fluorescence-based cell-based gel-based Activity-Based Protein Profiling (ABPP) IC50 for anti-target ABHD11 [AID504482, Type: confirmatory]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
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3
[SID99445332]
IC50 0.015Late stage assay provider results from the probe development effort to identify inhibitors of LYPLA1 and LYPLA2: Gel-based Activity-Based Protein Profiling (ABPP) IC50 for off-target ABHD11 [AID493154, Type: confirmatory]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
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4
[SID99445332]
IC50 0.015Late stage assay provider results from the probe development effort to identify inhibitors of LYPLA1: fluorescence-based biochemical gel-based Activity-Based Protein Profiling (ABPP) IC50 for anti-target ABHD11 Set 2 [AID504507, Type: confirmatory]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
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5
[SID99445332]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical gel-based ABPP inhibition and selectivity [AID493111_3, Type: other]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
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6
[SID99445332]
Late stage assay provider results from the probe development effort to identify inhibitors of LYPLA1: fluorescence-based biochemical gel-based Activity-Based Protein Profiling (ABPP) inhibition and selectivity [AID504520_1, Type: other]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
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7
[SID99445332]
Late stage assay provider results from the probe development effort to identify inhibitors of LYPLA1: fluorescence-based cell-based gel-based Activity-Based Protein Profiling (ABPP) percent inhibition for anti-target ABHD11 [AID504505, Type: other]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
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8
[SID99445332]
Late stage assay provider results from the probe development effort to identify inhibitors of ABHD11: Fluorescence-based biochemical gel-based Activity-Based Protein Profiling (ABPP) inhibition of the human isoform of ABHD11 [AID504892, Type: other]ABHD11 protein, partial [Homo sapiens] [gi:40226380]
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9
[SID99445332]
Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: fluorescence-based cell-based inhibition [AID493108_3, Type: other]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
View
10
[SID99445332]
Late stage assay provider results from the probe development effort to identify inhibitors of LYPLA1: LC-MS/MS assay to assess binding of compounds to active site of anti-target ABHD11 [AID504498, Type: other]Abhydrolase domain containing 11 [Homo sapiens] [gi:127798561]
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11
[SID99445332]
Late stage assay provider results from the probe development effort to identify inhibitors of LYPLA1: fluorescence-based biochemical gel-based Activity-Based Protein Profiling (ABPP) inhibition and selectivity [AID504520, Type: other]
View
12
[SID99445332]
0.000678Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_6, Type: summary]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
View
13
[SID99445332]
0.015Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_7, Type: summary]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
View
14
[SID99445332]
0.015Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_1, Type: summary]Abhydrolase domain containing 11 [Mus musculus] [gi:47682716]
View
15
[SID99445332]
10Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_2, Type: summary]Lypla1 [Mus musculus] [gi:71059731]
View
16
[SID99445332]
10Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_3, Type: summary]lysophospholipase 2 [Mus musculus] [gi:123122209]
View
17
[SID99445332]
50Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_4, Type: summary]
View
18
[SID99445332]
50Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_5, Type: summary]
View
19
[SID99445332]
50Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_8, Type: summary]
View
20
[SID99445332]
50Summary of probe development efforts to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2202_9, Type: summary]
View