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methyleugenol (CID 7127) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(11)
 
 
Inactive(865)
 
 
Inconclusive(29)
 
 
Unspecified(31)
 
 
Top Targets:
NR LBD PPAR(26)
 
 
 
7TM GPCR Srx(21)
 
 
NR LBD AR(18)
 
 
 
NR LBD ER(18)
 
 
 
 
7TM GPCR Srsx(15)
 
 
BioAssay Types:
Confirmatory(457)
 
 
 
 
 
Screening(355)
 
 
 
Literature(48)
 
 
 
 
Summary(48)
 
 
 
BioActivity Types:
Potency(422)
 
 
 
 
 
IC50(31)
 
 
 
EC50(8)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 752    Data Row: 936   Total Pages: 19   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103330682]
EC50 28Transactivation of PPAR expressed in HepG2 cells after 20 hrs by luminescence assay [AID655420, Type: Literature]
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2
[SID17388908]
Potency 33.4915qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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3
[SID103330682]
EC50 40Transactivation of GAL4-fused PPARgamma LBD expressed in HepG2 cells after 20 hrs by luminescence assay [AID655422, Type: Literature]
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4
[SID103330682]
EC50 46.5Transactivation of GAL4-fused PPARalpha LBD expressed in HepG2 cells after 20 hrs by luminescence assay [AID655421, Type: Literature]
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5
[SID144209545]
Potency-Replicate_1 61.7528qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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6
[SID49679141]
uHTS Fluorescent Assay Using Nedd8 Protein Substrate for Identification of Inhibitors of Sentrin-Specific Protease 8 (SENP8) [AID602440, Type: screening]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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7
[SID49679141]
Luminescence Microorganism Primary HTS to Identify Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID2716, Type: screening]
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8
[SID48414039]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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9
[SID48414039]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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10
[SID48414039]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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11
[SID48414039]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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12
[SID103330682]
EC50 50.6Transactivation of GAL4-fused PPARbeta LBD expressed in HepG2 cells after 20 hrs by luminescence assay [AID652614, Type: Literature]
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13
[SID103330682]
IC50 96.1Inhibition of soybean 15-lipoxygenase [AID392785, Type: Literature]
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14
[SID103330682]
IC50 96.1Inhibition of 15-lipoxygenase form soybean [AID395274, Type: Literature]
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15
[SID103330682]
IC50 100Inhibitory concentration of compound on nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages [AID248765, Type: Literature]
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16
[SID103330682]
Percent inhibition of nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages at 100 uM of compound [AID252044, Type: Literature]
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17
[SID103330682]
Antimicrobial activity Propionibacterium acnes ATCC 11827 after 2 days by broth dilution method [AID332912, Type: Literature]
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18
[SID103330682]
Antimicrobial activity against Bacillus subtilis ATCC 9372 after 2 days by twofold serial broth dilution method [AID334989, Type: Literature]
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19
[SID103330682]
Antimicrobial activity against Brevibacterium ammoniagenes ATCC 6872 after 2 days by twofold serial broth dilution method [AID334990, Type: Literature]
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20
[SID103330682]
Antimicrobial activity against Propionibacterium acnes ATCC 11827 after 2 days by twofold serial broth dilution method [AID334991, Type: Literature]
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21
[SID103330682]
Antimicrobial activity against Staphylococcus aureus ATCC 12598 after 2 days by twofold serial broth dilution method [AID334992, Type: Literature]
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22
[SID103330682]
Antimicrobial activity against Streptococcus mutans ATCC 25175 after 2 days by twofold serial broth dilution method [AID334993, Type: Literature]
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23
[SID103330682]
Antimicrobial activity against Escherichia coli ATCC 9637 after 2 days by twofold serial broth dilution method [AID334994, Type: Literature]
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24
[SID103330682]
Antimicrobial activity against Pseudomonas aeruginosa ATCC 10145 after 2 days by twofold serial broth dilution method [AID334995, Type: Literature]
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25
[SID103330682]
Antimicrobial activity against Enterobacter aerogenes ATCC 13048 after 2 days by twofold serial broth dilution method [AID334996, Type: Literature]
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26
[SID103330682]
Antimicrobial activity against Saccharomyces cerevisiae ATCC 7754 after 2 days by twofold serial broth dilution method [AID334997, Type: Literature]
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27
[SID103330682]
Antimicrobial activity against Candida utilis ATCC 9226 after 2 days by twofold serial broth dilution method [AID334998, Type: Literature]
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28
[SID103330682]
Antimicrobial activity against Pityrosporum ovale ATCC 14521 by twofold serial broth dilution method [AID334999, Type: Literature]
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29
[SID103330682]
Antimicrobial activity against Penicillium chrysogenum ATCC 10106 after 5 days by twofold serial broth dilution method [AID335000, Type: Literature]
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30
[SID103330682]
Antifungal activity against Saccharomyces cerevisiae ATCC 7754 after 2 days by broth dilution method [AID337835, Type: Literature]
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31
[SID103330682]
Antifungal activity against Candida albicans ATCC 18804 after 2 days by broth dilution method [AID337836, Type: Literature]
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32
[SID103330682]
Antifungal activity against Pityrosporum ovale ATCC 14521 after 3 days by broth dilution method [AID337837, Type: Literature]
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33
[SID103330682]
Percentage inhibition against release of beta-hexosaminidase from RBL-2H3 cells at 100 uM from control [AID166551, Type: Literature]
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34
[SID103330682]
Cytotoxicity against human HepG2 cells by MTT assay [AID652615, Type: Literature]
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35
[SID17388908]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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36
[SID26753022]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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37
[SID49679141]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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38
[SID103330682]
Antifungal activity against Microsporum canis C 112 by agar dilution method [AID376055, Type: Literature]
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39
[SID103330682]
Antifungal activity against Microsporum gypseum C 115 by agar dilution method [AID376045, Type: Literature]
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40
[SID103330682]
Antifungal activity against Trichophyton mentagrophytes ATCC by agar dilution method [AID376046, Type: Literature]
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41
[SID103330682]
Antifungal activity against Trichophyton rubrum C 113 by agar dilution method [AID376047, Type: Literature]
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42
[SID103330682]
Antifungal activity against Epidermophyton floccosum C 114 by agar dilution method [AID376048, Type: Literature]
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43
[SID144210391]
Potency-Replicate_1 1.9499qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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44
[SID49679141]
Potency 6.3096qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent) [AID485341, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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45
[SID49679141]
Potency 35.4813qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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46
[SID49679141]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
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47
[SID49679141]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide [AID1766, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
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48
[SID49679141]
Primary cell-based high-throughput screening assay for identification of compounds that potentiate KCNQ2 potassium channels [AID2239, Type: screening]potassium voltage-gated channel subfamily KQT member 2 [Rattus norvegicus] [gi:18959272]
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49
[SID49679141]
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ2 potassium channels [AID2156, Type: screening]potassium voltage-gated channel subfamily KQT member 2 [Rattus norvegicus] [gi:18959272]
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50
[SID49679141]
Potency qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation [AID540263, Type: confirmatory]importin subunit beta-1 isoform 1 [Homo sapiens] [gi:19923142]
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