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benzidine (CID 7111) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(17)
 
 
Inactive(597)
 
 
Inconclusive(39)
 
 
Unspecified(17)
 
 
Top Targets:
7tm 4(23)
 
 
NR LBD PPAR(21)
 
 
 
NR LBD ER(16)
 
 
 
NR LBD AR(16)
 
 
 
NR LBD VDR(11)
 
 
 
BioAssay Types:
Confirmatory(354)
 
 
 
 
 
Screening(222)
 
 
 
Summary(48)
 
 
 
 
Literature(27)
 
 
 
 
BioActivity Types:
Potency(347)
 
 
 
 
 
IC50(8)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 535    Data Row: 670   Total Pages: 34   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179072]
IC50 1.42In vitro antitrypanosomal activity against Trypanosoma brucei rhodesiense [AID213470, Type: Literature]
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2
[SID87334335]
IC50 7.39Discovery of small molecule inhibitors of the oncogenic and cytokinetic protein MgcRacGAP - Primary and Confirmatory Screens [AID624330, Type: confirmatory]rac GTPase-activating protein 1 [Homo sapiens] [gi:21361397]
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3
[SID87334335]
IC50 8Discovery of small molecule inhibitors of the oncogenic and cytokinetic protein MgcRacGAP - Counter Screen Coupled Enzyme [AID624351, Type: confirmatory]
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4
[SID144209557]
Potency-Replicate_1 9.5803qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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5
[SID144210723]
AhR Potency (uM) 10.4614qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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6
[SID144209557]
AhR Potency (uM) 16.395qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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7
[SID144210723]
Ratio Potency (uM) 24.3365qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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8
[SID144209557]
ATAD5 Potency (uM) 60.4474qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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9
[SID144210723]
Potency-Replicate_1 61.1306qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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10
[SID144210723]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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11
[SID144209557]
Ratio Potency (uM) 67.8231qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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12
[SID48413267]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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13
[SID48413267]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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14
[SID48413267]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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15
[SID48413267]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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16
[SID48413267]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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17
[SID87334335]
QFRET-based biochemical high throughput primary assay to identify inhibitors of human group III secreted phospholipase A2 enzyme (HGIII-sPLA2) [AID743126, Type: screening]phospholipase A2, group III [Homo sapiens] [gi:119580345]
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18
[SID103179072]
IC50 217Cytotoxic activity against rat L6 cells [AID99665, Type: Literature]
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19
[SID103179072]
Km 460Binding affinity against human UDP Glucuronosyltransferase 1A4 (UGT1A4) [AID214939, Type: Literature]
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20
[SID103179072]
Ratio of cytotoxicity against L6 cells to that of antitrypanosomal activity against Trypanosoma brucei rhodesiense [AID231796, Type: Literature]
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