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BioActivity Data for Compound acetylleucine (CID 70912)

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BioActivity Outcomes:
Inactive(238)
 
 
Inconclusive(31)
 
 
Unspecified(15)
 
 
Top Targets:
p450(11)
 
 
NR LBD PPAR(8)
 
 
 
NR LBD ER(7)
 
 
 
NR LBD AR(7)
 
 
NR LBD GR(6)
 
 
BioAssay Types:
Confirmatory(170)
 
 
 
Summary(24)
 
 
Screening(22)
 
 
Literature(8)
 
 
 
BioActivity Types:
Potency(159)
 
 
 
AC50(3)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 261    Data Row: 284   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID8149784]
Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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2
[SID8149784]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubU) [AID1593, Type: other]
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3
[SID8149784]
Screen for compounds that correct neuronal dysfunction without cell death as induced by the expression of polyglutamine-expanded, N-terminal huntingtin in C. elegans mechanosensory neurons (HDELENEU) [AID1599, Type: other]
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4
[SID8149784]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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5
[SID8149784]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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6
[SID8149784]
Screening of compounds showing protective effect against cell death induced by familial amyotrophic lateral sclerosis (FALS)-linked mutantsuperoxide dismutase 1 (SOD1) (ALSOD1) [AID1605, Type: other]
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7
[SID8149784]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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8
[SID8149784]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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9
[SID8149784]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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10
[SID8149784]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH) [AID1616, Type: other]
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11
[SID11112472]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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12
[SID103241545]
Partition coefficient (logP) [AID26797, Type: Literature]
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13
[SID103241545]
Bitter threshold value [AID233318, Type: Literature]
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14
[SID103241545]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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15
[SID103241545]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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16
[SID11112472]
Potency 6.3096qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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17
[SID170466209]
Ac50 7.94328qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel [AID1117310, Type: confirmatory]
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18
[SID170466209]
Ac50 qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
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19
[SID170466209]
Ac50 qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, blue channel [AID1117314, Type: confirmatory]
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20
[SID11112472]
Potency qHTS Assay for Inhibitors of Firefly Luciferase [AID411, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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