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CHEMBL2029010 (CID 70694098) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(5)
 
 
Unspecified(1)
 
 
BioAssay Types:
Literature(11)
 
 
 
 
BioActivity Types:
EC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 11    Data Row: 11   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID160699889]
EC50 9.4Agonist activity at human P2Y purinoceptor 4 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluorimetry [AID647895, Type: Literature]P2Y purinoceptor 4 [gi:1709524]
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2
[SID160699889]
EC50 24.6Agonist activity at human P2Y purinoceptor 2 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluorimetry [AID647894, Type: Literature]P2Y purinoceptor 2 [gi:311033490]
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3
[SID160699889]
EC50 36.1Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluorimetry [AID647896, Type: Literature]P2Y purinoceptor 6 [gi:2495019]
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4
[SID160699889]
Agonist activity at turkey P2Y purinoceptor 1 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration at 100 uM by spectrofluorimetry [AID647897, Type: Literature]P2Y purinoceptor 1 [gi:1352693]
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5
[SID160699889]
Agonist activity at human P2Y purinoceptor 2 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration at 100 uM by spectrofluorimetry [AID647898, Type: Literature]P2Y purinoceptor 2 [gi:311033490]
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6
[SID160699889]
Stability of the compound assessed as human e-NPP1-mediated hydrolysis at pH 8.5 after 20 mins by HPLC analysis [AID644880, Type: Literature]
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7
[SID160699889]
Antagonist activity at human P2Y purinoceptor 4 expressed in human 1321N1 cells assessed as inhibition of UTP-induced increase in intracellular calcium concentration by spectrofluorimetry [AID644878, Type: Literature]P2Y purinoceptor 4 [gi:1709524]
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8
[SID160699889]
Antagonist activity at turkey P2Y purinoceptor 1 expressed in human 1321N1 cells assessed as inhibition of 2-Sme-ADP-induced increase in intracellular calcium concentration by spectrofluorimetry [AID644876, Type: Literature]P2Y purinoceptor 1 [gi:1352693]
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9
[SID160699889]
EC50 Agonist activity at turkey P2Y purinoceptor 1 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluorimetry [AID647893, Type: Literature]P2Y purinoceptor 1 [gi:1352693]
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10
[SID160699889]
Antagonist activity at human P2Y purinoceptor 2 expressed in human 1321N1 cells assessed as inhibition of UTP-induced increase in intracellular calcium concentration by spectrofluorimetry [AID644877, Type: Literature]P2Y purinoceptor 2 [gi:311033490]
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11
[SID160699889]
Antagonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as inhibition of UDP-induced increase in intracellular calcium concentration by spectrofluorimetry [AID644879, Type: Literature]P2Y purinoceptor 6 [gi:2495019]
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