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CHEMBL2028997 (CID 70685720) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Unspecified(6)
 
 
Top Targets:
7TM GPCR Srsx(2)
 
 
 
BioAssay Types:
Literature(12)
 
 
 
BioActivity Types:
IC50(3)
 
 
Ki(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 12    Data Row: 12   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID160678353]
Ki 0.00023Compound was evaluated for the inhibition of [3H]bremazocine binding to Opioid receptor kappa 1 in guinea pig cerebellum membrane homogenates. [AID148827, Type: Literature]Kappa-type opioid receptor [gi:730228]
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2
[SID160678353]
IC50 0.00028Compound was evaluated for the agonistic activity against Opioid receptor mu 1 in guinea pig ileum. [AID149737, Type: Literature]Mu-type opioid receptor [gi:3024265]
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3
[SID160678353]
Ki 0.00155Compound was evaluated for the inhibition of [3H]DAGO([[3H]D-Ala,MePhe4,Glyol5]enkephalin) binding to mu sites in rat brain homogenates. [AID151469, Type: Literature]
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4
[SID160678353]
IC50 0.00307Compound was evaluated for the agonistic activity against Opioid receptor kappa 1 in rabbit vas deferens. [AID148431, Type: Literature]
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5
[SID160678353]
Ki 0.0063Compound was evaluated for the inhibition of [3H]DSLET([[3H]D-Ser2,Leu5,Thr6]enkephalin binding to Opioid receptor delta 1 in rat brain homogenates. [AID149535, Type: Literature]
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6
[SID160678353]
IC50 0.262Compound was evaluated for the agonistic activity against Opioid receptor delta 1 in hamster vas deferens. [AID147940, Type: Literature]
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7
[SID160678353]
Hill coefficient value was measured against mu sites in rat brain homogenates [AID151295, Type: Literature]
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8
[SID160678353]
Hill coefficient value was measured against Opioid receptor kappa 1 in guinea pig cerebellum membrane homogenates [AID148550, Type: Literature]Kappa-type opioid receptor [gi:730228]
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9
[SID160678353]
Hill coefficient value was measured against delta sites in rat brain homogenates [AID149396, Type: Literature]
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10
[SID160678353]
Receptor selectivity index is the ratio of the apparent KI at delta opioid receptor over the apparent KI at the highest affinity site [AID231575, Type: Literature]
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11
[SID160678353]
Receptor selectivity index is the ratio of the apparent KI at kappa opioid receptor over the apparent KI at the highest affinity site [AID231576, Type: Literature]
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12
[SID160678353]
Receptor selectivity index is the ratio of the apparent KI at mu opioid receptor over the apparent KI at the highest affinity site [AID231577, Type: Literature]
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