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MLS004829573 (CID 70680663) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(6)
 
 
Top Targets:
PKS(6)
 
 
BioAssay Types:
Confirmatory(6)
 
 
BioActivity Types:
IC50(6)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 4    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID161004965]
IC50_FAS-TE (OMFH - kinetic)_Mean 0.152SAR confirmation of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a kinetic, fluorescence intensity assay, round 2 [AID652286, Type: confirmatory]fatty acid synthase [Homo sapiens] [gi:41872631]
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2
[SID161004965]
IC50_FAS-TE (OMFH)_Mean 0.154SAR confirmation of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay, round 2 [AID652287, Type: confirmatory]fatty acid synthase [Homo sapiens] [gi:41872631]
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3
[SID160658398]
IC50_FAS-TE (OMFH - kinetic)_Mean 0.296SAR confirmation of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a kinetic, fluorescence intensity assay [AID652165, Type: confirmatory]fatty acid synthase [Homo sapiens] [gi:41872631]
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4
[SID160658398]
IC50_FAS-TE (OMFH)_Mean 0.3SAR confirmation of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay [AID652164, Type: confirmatory]fatty acid synthase [Homo sapiens] [gi:41872631]
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5
[SID160658398]
IC50_FAS-TE (OMFH - kinetic)_Mean 1.06SAR confirmation of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a kinetic, fluorescence intensity assay, round 2 [AID652286, Type: confirmatory]fatty acid synthase [Homo sapiens] [gi:41872631]
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6
[SID160658398]
IC50_FAS-TE (OMFH)_Mean 1.13SAR confirmation of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay, round 2 [AID652287, Type: confirmatory]fatty acid synthase [Homo sapiens] [gi:41872631]
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