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xanthone (CID 7020) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Inactive(285)
 
 
Inconclusive(26)
 
 
Unspecified(21)
 
 
Top Targets:
7tm 4(11)
 
 
NR LBD PPAR(8)
 
 
NR LBD ER(7)
 
 
 
 
NR LBD AR(7)
 
 
 
NR LBD TR(5)
 
 
BioAssay Types:
Screening(136)
 
 
Confirmatory(131)
 
 
 
 
Literature(35)
 
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(145)
 
 
 
 
IC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 323    Data Row: 340   Total Pages: 17   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103453512]
IC50 0.84Concentration required to inhibit monoamine oxidase activity by 50% [AID240726, Type: Literature]
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2
[SID26749494]
Potency 12.5893qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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3
[SID26749494]
Potency 25.1189qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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4
[SID26749494]
Potency 25.1189qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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5
[SID144211468]
Potency-Replicate_1 48.5577qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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6
[SID144211468]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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7
[SID103453512]
IC50 Antiviral activity against JC polyomavirus M1/SVEdelta infected in human SVG-A cells assessed as inhibition of viral replication after 3 days [AID558029, Type: Literature]
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8
[SID144211468]
AhR Potency (uM) qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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9
[SID103453512]
TC50 40Cytotoxicity against human SVG-A cells [AID558037, Type: Literature]
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10
[SID103453512]
IC50 500Cytotoxicity against human DU145 cells after 48 hrs [AID459914, Type: Literature]
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11
[SID103453512]
IC50 500Cytotoxicity against human MCF7 cells after 48 hrs [AID459915, Type: Literature]
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12
[SID103453512]
IC50 500Cytotoxicity against human HeLa cells after 48 hrs [AID459916, Type: Literature]
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13
[SID103453512]
Antifungal activity against Alternaria tenuis at 1 ppm after 168 hrs at 24 hrs intervals [AID398906, Type: Literature]
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14
[SID103453512]
Antifungal activity against Alternaria tenuis at 10 ppm after 168 hrs at 24 hrs intervals [AID398907, Type: Literature]
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15
[SID103453512]
Antifungal activity against Alternaria tenuis at 100 ppm after 168 hrs at 24 hrs intervals [AID398908, Type: Literature]
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16
[SID103453512]
Antifungal activity against Alternaria tenuis at 1000 ppm after 168 hrs at 24 hrs intervals [AID398909, Type: Literature]
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17
[SID103453512]
Antifungal activity against Drechslera oryzae at 1 ppm after 168 hrs at 24 hrs intervals [AID398910, Type: Literature]
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18
[SID103453512]
Antifungal activity against Drechslera oryzae at 10 ppm after 168 hrs at 24 hrs intervals [AID399161, Type: Literature]
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19
[SID103453512]
Antifungal activity against Drechslera oryzae at 100 ppm after 168 hrs at 24 hrs intervals [AID399162, Type: Literature]
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20
[SID103453512]
Antifungal activity against Drechslera oryzae at 1000 ppm after 168 hrs at 24 hrs intervals [AID399163, Type: Literature]
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