Bookmark and Share
Aminacrine (CID 7019) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(23)
 
 
Inactive(69)
 
 
Inconclusive(23)
 
 
Unspecified(36)
 
 
Top Targets:
PLDc mTdp1 2(3)
 
 
 
NR LBD TR(2)
 
 
STKc ERK1 2 l..(2)
 
 
BRCT(2)
 
 
ANK(2)
 
 
BioAssay Types:
Confirmatory(71)
 
 
 
 
 
Literature(52)
 
 
 
 
 
Screening(12)
 
 
 
BioActivity Types:
Potency(68)
 
 
 
 
IC50(4)
 
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 142    Data Row: 151   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103217574]
ID50 1.9In vitro inhibitory dose that reduces L1210 cell line by 50% when added for a period of 70h [AID96818, Type: Literature]
View
2
[SID103217574]
GI50 2Growth inhibition of human HL60 cells [AID539397, Type: Literature]
View
3
[SID103217574]
IC50 2.14Cytotoxic effect in human peripheral blood monocyte cells(PBMC) [AID152935, Type: Literature]
View
4
[SID103217574]
IC50 2.6Evaluated for concentration which when added to cultures of L1210 leukemia cells for a period of 70 hr reduces cell numbers of 50% of control cultures [AID98315, Type: Literature]
View
5
[SID26748404]
Potency 3.2643qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
6
[SID26748404]
Potency 3.6626qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
7
[SID26748404]
Potency 15.8489qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1: Spectroscopic Profiling in AFC Spectral Region [AID923, Type: confirmatory]
View
8
[SID26748404]
Potency 31.6228qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
View
9
[SID26748404]
Potency 31.6228qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
View
10
[SID26748404]
Potency 31.6228qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
View
11
[SID103217574]
Ki 38The competitive inhibitory activity against trypanothione reductase was evaluated from Lineweaver Burk plots [AID214657, Type: Literature]Trypanothione reductase [gi:136620]
View
12
[SID103217574]
Binding affinity to amyloid beta (1 to 42) fibrils by change in fluorescence at 100 uM after 10 mins [AID475504, Type: Literature]
View
13
[SID103217574]
Binding affinity to amyloid beta (1 to 42) oligomers by change in fluorescence at 100 uM after 10 mins [AID475505, Type: Literature]
View
14
[SID103217574]
Cytotoxicity against mouse ScN2a cells assessed as maximal tolerant concentration [AID344297, Type: Literature]
View
15
[SID77577]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
View
16
[SID77577]
NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
View
17
[SID77577]
NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
View
18
[SID77577]
NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
View
19
[SID77577]
NCI Yeast Anticancer Drug Screen. Data for the bub3 strain [AID167, Type: other]
View
20
[SID77577]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
View