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1-methylnaphthalene (CID 7002) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(378)
 
 
Inconclusive(15)
 
 
Unspecified(4)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD ER(16)
 
 
 
NR LBD AR(16)
 
 
 
p450(10)
 
 
 
 
NR LBD Fxr(10)
 
 
 
BioAssay Types:
Confirmatory(274)
 
 
 
Screening(51)
 
 
Summary(48)
 
 
 
 
Literature(9)
 
 
 
 
BioActivity Types:
Potency(274)
 
 
 
 
IC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 301    Data Row: 402   Total Pages: 21   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103463857]
IC50 23.9883Inhibition of mouse CYP2A5 [AID420670, Type: Literature]Cytochrome P450 2A5 [gi:117196]
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2
[SID103463857]
IC50 24Inhibitory concentration against mouse cytochrome P450 2A5 [AID241174, Type: Literature]
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3
[SID103463857]
IC50 33.9625Inhibition of human CYP2A6 [AID420671, Type: Literature]Cytochrome P450 2A6 [gi:308153612]
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4
[SID103463857]
IC50 34Inhibitory concentration against human cytochrome P450 2A6 [AID241172, Type: Literature]Cytochrome P450 2A6 [gi:308153612]
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5
[SID144208966]
AhR Potency (uM) qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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6
[SID103463857]
IC50 110Inhibitory concentration against recombinant human cytochrome P450 1A2 [AID241334, Type: Literature]Cytochrome P450 1A2 [gi:117144]
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7
[SID103463857]
Ratio of IC50 for human CYP2A6 to that of mouse CYP2A5 was determined [AID242975, Type: Literature]
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8
[SID103463857]
Octanol-water partition coefficient, log P of the compound [AID603957, Type: Literature]
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9
[SID17389821]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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10
[SID17389821]
Potency 5.9557qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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11
[SID17389821]
Potency 39.8107qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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12
[SID17389821]
Potency qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
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13
[SID99355599]
Primary biochemical fluorescence polarization-based high throughput screening assay to identify inhibitors of protein arginine methyltransferase 1 (PRMT1) [AID652257, Type: screening]PRMT1 protein [Homo sapiens] [gi:32425330]
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14
[SID17389821]
Potency qHTS Assay for Identification of Small Molecule Inducers of Hypoxia Response [AID2120, Type: confirmatory]hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) [Homo sapiens] [gi:32879895]
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15
[SID17389821]
qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore) [AID880, Type: confirmatory]guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 [Homo sapiens] [gi:33946324]
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16
[SID17389821]
Potency qHTS assay for small molecule activators of the nuclear factor-kappa B (NF-kB) signaling pathway [AID651749, Type: confirmatory]nuclear factor NF-kappa-B p105 subunit isoform 1 [Homo sapiens] [gi:34577122]
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17
[SID17389821]
Potency qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID926, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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18
[SID17389821]
Potency qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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19
[SID17389821]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase 1 [gi:44888968]
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20
[SID99355599]
S100A4: HTS Measured in Biochemical System Using Plate Reader - 7045-01_Inhibitor_SinglePoint_HTS_Activity [AID652163, Type: screening]S100A4 [Homo sapiens] [gi:47496637]
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