Bookmark and Share
SMR000030131 (CID 6997825) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(58)
 
 
Inactive(792)
 
 
Inconclusive(22)
 
 
Unspecified(6)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
 
7TM GPCR Srsx(22)
 
 
 
alkPPc(16)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
BioAssay Types:
Screening(571)
 
 
 
 
 
Confirmatory(283)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(171)
 
 
 
 
 
IC50(62)
 
 
 
 
EC50(19)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 804    Data Row: 878   Total Pages: 18   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID51089649]
AbsAC26_uM 0.0584Luciferase Reporter Cell Based HTS to identify inhibitors of N-linked Glycosylation Measured in Cell-Based System Using Plate Reader - 2146-01_Inhibitor_Dose_CherryPick_Activity [AID624491, Type: confirmatory]
View
2
[SID4248242]
IC50_Mean 0.22Dose response counterscreen of uHTS chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation in a HEK-293T cell line using a luminescence assay [AID489041, Type: confirmatory]
View
3
[SID4248242]
Potency 0.3264A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
View
4
[SID4248242]
Potency 0.4611qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
View
5
[SID4248242]
Potency 0.5805A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
View
6
[SID4248242]
Potency 0.5805qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
7
[SID4248242]
Potency 0.8199qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
8
[SID4248242]
EC50 0.85Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to DRD Non-Viral Oncogenic Fibroblast [AID1934, Type: confirmatory]
View
9
[SID4248242]
EC50 1.074Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to BJ-TERT RAS-Independent Fibroblast [AID1933, Type: confirmatory]
View
10
[SID4248242]
EC50 1.103Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to BJ-TERT-LT-ST RAS-Independent Fibroblast [AID1935, Type: confirmatory]
View
11
[SID4248242]
EC50 1.767Luminescence Cell-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to BJeLR RAS-Dependent Fibroblast [AID1936, Type: confirmatory]
View
12
[SID51089649]
IC50_TAG_Mean 3.3Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_1, Type: confirmatory]
View
13
[SID4248242]
Potency 3.5481qHTS Assay to Find Inhibitors of Chronic Active B-Cell Receptor Signaling [AID493014, Type: confirmatory]
View
14
[SID4248242]
Potency 5.6234qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
View
15
[SID4248242]
Potency 11.2202qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
View
16
[SID4248242]
Potency 11.2202qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens] [gi:56550039]
View
17
[SID51089649]
IC50_TAG_DAPI_Mean 25Dose Response confirmation of small molecule Triacylglycerol inhbitors in a panel assay [AID651630_4, Type: confirmatory]
View
18
[SID4248242]
Potency 25.1189qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent) [AID1476, Type: confirmatory]Chain A, Crystal Structure Of Cruzain Covalently Bound To A Purine Nitrile [gi:281307097]
View
19
[SID4248242]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
View
20
[SID4248242]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
View
21
[SID4248242]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
View
22
[SID4248242]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
View
23
[SID4248242]
Primary HTS assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) antagonists [AID612, Type: screening]5-hydroxytryptamine receptor 1A [Homo sapiens] [gi:55956923]
View
24
[SID4248242]
MLPCN maternal gene expression-MEX-5 TCR-2 binding assay-Primary Screen [AID1832, Type: screening]Zinc finger protein mex-5 [gi:55976631]
View
25
[SID4248242]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]BRCA1-associated RING domain protein 1 [gi:116241265]
View
26
[SID51089649]
uHTS identification of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651582, Type: screening]
View
27
[SID4248242]
Cell Proliferation & Viability (Cytotoxicity) Primary Assay 60K MLSMR [AID463, Type: screening]
View
28
[SID4248242]
Cell Proliferation & Viability (Cytotoxicity) Dose Response Assay 60K MLSMR [AID464, Type: confirmatory]
View
29
[SID4248242]
Primary HTS assay for chemical inhibitors of antigen receptor-induced NF-kappaB activation [AID465, Type: screening]
View
30
[SID4248242]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - inhibitors [AID1813, Type: screening]
View
31
[SID4248242]
EC50 Fluorescent HTS Cytotoxicity/Cell viability assay (HT1080 cells) [AID620, Type: confirmatory]
View
32
[SID4248242]
EC50 Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7 cells) [AID430, Type: confirmatory]
View
33
[SID4248242]
EC50 Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7K cells) [AID431, Type: confirmatory]
View
34
[SID4248242]
qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region [AID589, Type: other]
View
35
[SID4248242]
qHTS Assay for Spectroscopic Profiling in A350 Spectral Region [AID590, Type: other]
View
36
[SID4248242]
Leishmania major promastigote HTS [AID1063, Type: screening]
View
37
[SID4248242]
IL-1B Induced NFkB Translocation - Primary Screen [AID796, Type: screening]
View
38
[SID4248242]
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression [AID802, Type: screening]
View
39
[SID4248242]
Cell signaling CRE-BLA (Fsk stim) [AID662, Type: confirmatory]
View
40
[SID4248242]
Single concentration confirmation of chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation [AID435020, Type: screening]
View
41
[SID51089649]
Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_SinglePoint_HTS_Activity [AID488862, Type: screening]
View
42
[SID51089649]
Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_Dose_CherryPick_Activity_Set2 [AID504539, Type: confirmatory]
View
43
[SID51089649]
Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_SinglePoint_CherryPick_Activity [AID504592, Type: confirmatory]
View
44
[SID4248242]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Full-Length Luciferase Counterscreen assay [AID504607, Type: screening]
View
45
[SID4248242]
uHTS luminescence assay for the identification of chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation [AID435003, Type: screening]
View
46
[SID4248242]
Luminescence-based counterscreen assay for KLF5 inhibitors: cell-based high throughput screening assay to identify cytotoxic compounds using the IEC-6 intestinal epithelial cell line. [AID1825, Type: screening]
View
47
[SID4248242]
Primary Cell Based High Throughput Screening Assay for Antagonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) [AID571, Type: screening]5-hydroxytryptamine receptor 1E [gi:112822]
View
48
[SID4248242]
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment [AID2417, Type: screening]polypyrimidine tract-binding protein 1 isoform a [Homo sapiens] [gi:4506243]
View
49
[SID4248242]
Primary cell-based high throughput screening assay to measure STAT3 activation [AID871, Type: screening]STAT3 [Homo sapiens] [gi:13272532]
View
50
[SID4248242]
Primary screen for compounds that inhibit Alzheimer's amyloid precursor protein (APP) translation [AID1285, Type: screening]amyloid precursor protein [Homo sapiens] [gi:257380]
View