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BioActivity Data for Compound 2-nitroaniline (CID 6946)

BioActivity Outcomes:
Active(1)
 
 
Inactive(345)
 
 
Inconclusive(20)
 
 
Unspecified(13)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD ER(16)
 
 
NR LBD AR(16)
 
 
 
NR LBD VDR(10)
 
 
NR LBD TR(10)
 
 
 
BioAssay Types:
Confirmatory(294)
 
 
 
 
Summary(56)
 
 
 
Literature(13)
 
 
 
BioAssay Categories:
Toxicity(42)
 
 
 
ADME(9)
 
 
BioActivity Types:
Potency(302)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 267    Data Row: 379   Total Pages: 19   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213609]
Potency-Replicate_1 48.5577qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID17388826]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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3
[SID103176216]
Partition coefficient (logP) [AID23251, Type: Literature]
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4
[SID103176216]
Partition coefficient (logP) (benzene) [AID23252, Type: Literature]
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5
[SID103176216]
Partition coefficient (logP) (carbon tetrachloride) [AID23253, Type: Literature]
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6
[SID103176216]
Partition coefficient (logP) (chloroform) [AID23254, Type: Literature]
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7
[SID103176216]
Partition coefficient (logP) (ether) [AID23255, Type: Literature]
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8
[SID103176216]
Partition coefficient (logP) (hexane) [AID23256, Type: Literature]
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9
[SID103176216]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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10
[SID103176216]
Permeability coefficient through artificial membrane in presence of unstirred water layer by PAMPA [AID288184, Type: Literature]
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11
[SID103176216]
Permeability coefficient through artificial membrane in presence of stirred water layer [AID288185, Type: Literature]
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12
[SID103176216]
Partition coefficient, log P of the compound [AID288192, Type: Literature]
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13
[SID103176216]
Membrane retention in permeability experiment with artificial membrane [AID288191, Type: Literature]
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14
[SID103176216]
Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5 [AID1159387, Type: other]
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15
[SID144209569]
Potency-Replicate_1 27.5283qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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16
[SID144213609]
Potency-Replicate_1 61.1306qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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17
[SID144213609]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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18
[SID144209569]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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19
[SID144213609]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
20
[SID144209569]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View