Bookmark and Share
XCT790 (CID 6918788) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(13)
 
 
Inactive(109)
 
 
Inconclusive(15)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(5)
 
 
PIKKc TOR(4)
 
 
Pyr redox dim(4)
 
 
 
HELICc(3)
 
 
SIS(3)
 
 
BioAssay Types:
Confirmatory(91)
 
 
 
 
Screening(39)
 
 
Literature(8)
 
 
 
 
BioActivity Types:
Potency(92)
 
 
 
 
IC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 122    Data Row: 139   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103456869]
IC50 0.37Inhibition of estrogen-related receptor alpha Gal4 activity [AID241429, Type: Literature]
View
2
[SID103456869]
IC50 0.37Inverse agonist activity at GAL4-fused ERRalpha (unknown origin) transfected in african green monkey CV1 cells after 24 hrs by luciferase reporter gene assay [AID748012, Type: Literature]Steroid hormone receptor ERR1 [gi:215274146]
View
3
[SID103456869]
IC50 0.37Antagonist activity at ERRalpha LBD expressed in HEK293 cells assessed as Gal4-SRC2 interaction by two hybrid luciferase reporter gene assay [AID569736, Type: Literature]
View
4
[SID29217710]
Potency 6.7016qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
View
5
[SID90341312]
Potency 7.9433qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
View
6
[SID90341312]
Potency 8.4368qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
View
7
[SID29217710]
Potency 8.9125qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
View
8
[SID90341312]
Potency 10.6213qHTS Validation Assay for the Inhibitors of DNA Replication in Gram-Positive Bacteria [AID485295, Type: confirmatory]DNA polymerase III, partial [Bacillus subtilis] [gi:30027657]
View
9
[SID90341312]
Potency 14.575qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
View
10
[SID90341312]
Potency 18.8876Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS [AID504845, Type: confirmatory]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301163]
View
11
[SID90341312]
Potency 23.9341qHTS Validation Assay to Find Inhibitors of Pin1 [AID504536, Type: confirmatory]peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Homo sapiens] [gi:5453898]
View
12
[SID90341312]
Potency 50.1187Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein, partial [Homo sapiens] [gi:118600387]
View
13
[SID90341312]
Potency 89.1251qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID488953, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
View
14
[SID103456869]
Inverse agonist activity at GAL4-fused ERRalpha (unknown origin) transfected in african green monkey CV1 cells at 1 uM after 24 hrs by luciferase reporter gene assay relative to control [AID748035, Type: Literature]Steroid hormone receptor ERR1 [gi:215274146]
View
15
[SID103456869]
Percent inhibition of estrogen-related receptor alpha Gal4 activity at 10 uM [AID243558, Type: Literature]
View
16
[SID90341312]
Potency 2.5928HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Potentiators [AID488982, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
View
17
[SID29217710]
Potency 3.9811qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
View
18
[SID29217710]
Potency 3.9811qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens] [gi:56550039]
View
19
[SID90341312]
Potency 4.6109qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
View
20
[SID90341312]
Potency 7.5193qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
View