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halobetasol (CID 6918178) - Compound BioActivity Data
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BioActivity Outcomes:
Active(16)
 
 
Inactive(33)
 
 
Inconclusive(19)
 
 
Unspecified(14)
 
 
Top Targets:
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
NR LBD GR(6)
 
 
 
NR LBD TR(3)
 
 
 
 
7TM GPCR Srsx(2)
 
 
BioAssay Types:
Confirmatory(49)
 
 
 
 
Literature(16)
 
 
 
Summary(15)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(62)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 81    Data Row: 82   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144206008]
Ratio Potency (uM) 0.00065081qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720719, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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2
[SID144206008]
Potency-Replicate_1 0.0007qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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3
[SID144206008]
Ratio Potency (uM) 0.952052qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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4
[SID144206008]
Potency-Replicate_1 1.693qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway [AID743036, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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5
[SID144206008]
Potency-Replicate_1 3.3491qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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6
[SID144206008]
Potency-Replicate_1 7.4978qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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7
[SID144206008]
Potency-Replicate_1 11.8832qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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8
[SID144206008]
Potency-Replicate_1 11.8832qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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9
[SID144206008]
Ratio Potency (uM) 11.9856qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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10
[SID144206008]
Ratio Potency (uM) 15.184qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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11
[SID144206008]
Potency 18.8375qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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12
[SID144206008]
Potency-Replicate_1 21.3138qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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13
[SID144206008]
Potency-Replicate_1 23.7101qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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14
[SID144206008]
TR Potency (uM) 33.4915qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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15
[SID103770891]
Glucocorticoid receptor agonist [AID742932, Type: Literature]Glucocorticoid receptor [gi:121069]
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16
[SID103770891]
Glucocorticoid receptor agonist [AID742932, Type: Literature]Glucocorticoid receptor [gi:121069]
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17
[SID103770891]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia [AID625279, Type: Literature]
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18
[SID103770891]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis [AID625280, Type: Literature]
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19
[SID103770891]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis [AID625281, Type: Literature]
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20
[SID103770891]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis [AID625282, Type: Literature]
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