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ciclesonide (CID 6918155) - Compound BioActivity Data
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BioActivity Outcomes:
Active(10)
 
 
Inactive(41)
 
 
Inconclusive(16)
 
 
Unspecified(14)
 
 
Top Targets:
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
 
NR LBD GR(5)
 
 
 
NR LBD TR(3)
 
 
 
 
7TM GPCR Srsx(2)
 
 
BioAssay Types:
Confirmatory(49)
 
 
 
 
Literature(15)
 
 
 
Summary(15)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(62)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 81    Data Row: 81   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144206039]
Ratio Potency (uM) 0.0126432qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720719, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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2
[SID144206039]
Potency-Replicate_1 0.0133qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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3
[SID144206039]
Potency-Replicate_1 7.8396qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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4
[SID144206039]
Ratio Potency (uM) 7.90777qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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5
[SID144206039]
Potency-Replicate_1 10.5909qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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6
[SID144206039]
Potency-Replicate_1 18.8336qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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7
[SID144206039]
Potency-Replicate_1 21.3138qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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8
[SID144206039]
Ratio Potency (uM) 22.5767qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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9
[SID144206039]
Potency 28.1838qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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10
[SID160668474]
Glucocorticoid receptor agonist [AID742932, Type: Literature]Glucocorticoid receptor [gi:121069]
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11
[SID160668474]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia [AID625279, Type: Literature]
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12
[SID160668474]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis [AID625280, Type: Literature]
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13
[SID160668474]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis [AID625281, Type: Literature]
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14
[SID160668474]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis [AID625282, Type: Literature]
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15
[SID160668474]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests [AID625283, Type: Literature]
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16
[SID160668474]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure [AID625284, Type: Literature]
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17
[SID160668474]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic necrosis [AID625285, Type: Literature]
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18
[SID160668474]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatitis [AID625286, Type: Literature]
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19
[SID160668474]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatomegaly [AID625287, Type: Literature]
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20
[SID160668474]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for jaundice [AID625288, Type: Literature]
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