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T5235155 (CID 6892904) - Compound BioActivity Data
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BioActivity Outcomes:
Active(94)
 
 
Inactive(649)
 
 
Inconclusive(39)
 
 
Unspecified(3)
 
 
Top Targets:
7tm 4(40)
 
 
 
Bcl-2 like(16)
 
 
 
alkPPc(12)
 
 
Tryp SPc(10)
 
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(524)
 
 
 
 
 
Confirmatory(235)
 
 
 
 
 
Literature(12)
 
 
 
BioActivity Types:
Potency(165)
 
 
 
 
 
IC50(56)
 
 
 
EC50(9)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 710    Data Row: 785   Total Pages: 40   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID89852552]
Potency 0.8913qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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2
[SID89852552]
Potency 1.2589qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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3
[SID17385775]
IC50 1.63275Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors [AID1417, Type: confirmatory]Mcl-1 [Homo sapiens] [gi:7582271]
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4
[SID17385775]
IC50 2.21AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation [AID2018, Type: confirmatory]SUMO-conjugating enzyme UBC9 [Homo sapiens] [gi:4507785]
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5
[SID17385775]
IC50 2.21AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation [AID2018, Type: confirmatory]SUMO1 activating enzyme subunit 1 [Homo sapiens] [gi:17390638]
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6
[SID17385775]
IC50 2.21AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation [AID2018, Type: confirmatory]Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi:13111961]
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7
[SID17385775]
Potency 3.5481qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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8
[SID89852552]
Potency 3.7686qHTS for Inhibitors of Polymerase Kappa: Confirmatory Assay for Cherry-picked Compounds [AID720501, Type: Literature]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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9
[SID17385775]
Potency 3.9811CHOP2 Reporter Counterscreen Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID493169, Type: confirmatory]enteropeptidase precursor [Homo sapiens] [gi:223942069]
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10
[SID17385775]
IC50 4.03Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide. [AID2217, Type: confirmatory]Myeloid cell leukemia sequence 1 (BCL2-related) [Homo sapiens] [gi:78070770]
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11
[SID89852552]
Potency 4.4668qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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12
[SID17385775]
Potency 4.4668Ub-rhodamine 110 based assay for inhibitors Ubiquitin-specific Protease USP2a [AID493170, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
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13
[SID89852552]
Potency 4.7755qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds [AID720502, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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14
[SID17385775]
IC50 5.36uHTS fluorescence assay for the identification of Human Immunodeficiency Virus Fusion Inhibitors. [AID1986, Type: confirmatory]envelope glycoprotein [Human immunodeficiency virus 1] [gi:45357394]
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15
[SID89852552]
IC50_Mean 5.98Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. [AID504756, Type: confirmatory]cysteine protease ATG4B isoform a [Homo sapiens] [gi:47132611]
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16
[SID89852552]
Potency 6.8061qHTS for Inhibitors of WRN Helicase: Confirmatory Assay for Cherry-picked Compounds. [AID720497, Type: confirmatory]WRN [Homo sapiens] [gi:3719421]
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17
[SID89852552]
Potency 8.9125qHTS for Inhibitors of WRN Helicase [AID651768, Type: confirmatory]WRN [Homo sapiens] [gi:3719421]
View
18
[SID17385775]
Potency 9.2683Confirmation Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter [AID493168, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
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19
[SID17385775]
IC50_Artemis_Mean 11.4Dose Response confirmation of small molecule inhibitors originally identified via uHTS of Artemis endonuclease activity via a fluorescence intensity assay [AID720701, Type: confirmatory]protein artemis isoform a [Homo sapiens] [gi:76496497]
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20
[SID17385775]
IC50 12.4uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi:13111961]
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