MLS000068794 (CID 6882260) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(25)
 
 
Inactive(701)
 
 
Inconclusive(12)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(18)
 
 
alkPPc(18)
 
 
Bcl-2 like(11)
 
 
Tryp SPc(11)
 
 
7TM GPCR Srsx(10)
 
 
BioAssay Types:
Screening(488)
 
 
 
Confirmatory(228)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(148)
 
 
 
 
 
IC50(45)
 
 
EC50(12)
 
 
AC50(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 739    Data Row: 739   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID857395]
AbsAC40_uM 1.407MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_Dose_CherryPick_Activity [AID540258, Type: confirmatory]
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2
[SID857395]
Potency 2.2387qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
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3
[SID857395]
Potency 2.2387qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
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4
[SID857395]
Potency 2.2387qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]RAB9A gene product [Homo sapiens] [gi:4759012]
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5
[SID857395]
Potency 2.6122qHTS Assay for Modulators of miRNAs and/or Inhibitors of miR-21 [AID2289, Type: confirmatory]
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6
[SID857395]
Potency 2.8184qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]NPC1 gene product [Homo sapiens] [gi:255652944]
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7
[SID857395]
Potency 6.7456qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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8
[SID857395]
Potency 12.5893qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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9
[SID857395]
Potency 12.5893qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
10
[SID857395]
Potency 20.5962qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504466, Type: confirmatory]ATAD5 protein [Homo sapiens] [gi:116283940]
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11
[SID857395]
Potency 25.1189qHTS Assay for Inhibitors of Firefly Luciferase [AID411, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
12
[SID857395]
 Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID560, Type: screening]Nuclear receptor ROR-alpha [gi:548814]
View
13
[SID857395]
 Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID560, Type: screening]Nuclear receptor ROR-alpha [gi:548814]
View
14
[SID857395]
 Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID560, Type: screening]Nuclear receptor ROR-alpha [gi:548814]
View
15
[SID857395]
 Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID560, Type: screening]Nuclear receptor ROR-alpha [gi:548814]
View
16
[SID857395]
 Primary cell-based high throughput screening assay to measure STAT1 activation [AID932, Type: screening]signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens] [gi:6274552]
View
17
[SID857395]
 Primary cell-based high throughput screening assay to measure STAT1 activation [AID932, Type: screening]signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens] [gi:6274552]
View
18
[SID857395]
 Confirmation cell-based high throughput screening assay to measure STAT1 activation [AID1262, Type: screening]signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens] [gi:6274552]
View
19
[SID857395]
 Confirmation cell-based high throughput screening assay to measure STAT1 activation [AID1262, Type: screening]signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens] [gi:6274552]
View
20
[SID857395]
 Counterscreen assay for STAT1 activators: Cell-based high throughput assay to measure NF-kappaB activation [AID1306, Type: screening]signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens] [gi:6274552]
View
21
[SID857395]
 Counterscreen assay for STAT1 activators: Cell-based high throughput assay to measure NF-kappaB activation [AID1306, Type: screening]signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens] [gi:6274552]
View
22
[SID857395]
 Counterscreen assay for STAT1 activators: Cell-based high throughput assay to measure STAT3 activation [AID1316, Type: screening]STAT3 [Homo sapiens] [gi:13272532]
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23
[SID857395]
 Counterscreen assay for STAT1 activators: Cell-based high throughput assay to measure STAT3 activation [AID1316, Type: screening]STAT3 [Homo sapiens] [gi:13272532]
View
24
[SID857395]
 Counterscreen assay for STAT1 activators: Cell-based high throughput assay to measure STAT3 activation [AID1316, Type: screening]STAT3 [Homo sapiens] [gi:13272532]
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25
[SID857395]
 MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint_HTS_Activity [AID588334, Type: screening]
View
26
[SID857395]
 Luminescent HTS for small molecule activators of MT1-MMP transcription [AID750, Type: screening]
View
27
[SID857395]
 MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
View
28
[SID857395]
 Luminescence-based primary cell-based high throughput screening assay to identify inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1) [AID504766, Type: screening]NR0B1 gene product [Homo sapiens] [gi:5016090]
View
29
[SID857395]
 Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) [AID2796, Type: screening]aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003]
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30
[SID857395]
 Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) [AID2796, Type: screening]aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003]
View
31
[SID857395]
 Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) [AID2796, Type: screening]aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003]
View
32
[SID857395]
 HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen [AID651550, Type: screening]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
33
[SID857395]
 HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen [AID651550, Type: screening]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
34
[SID857395]
 HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen [AID651550, Type: screening]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
35
[SID857395]
 Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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36
[SID857395]
 A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
View
37
[SID857395]
 High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]NFKB1 gene product [Homo sapiens] [gi:34577122]
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38
[SID857395]
 High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]NFKB1 gene product [Homo sapiens] [gi:34577122]
View
39
[SID857395]
 High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]NFKB1 gene product [Homo sapiens] [gi:34577122]
View
40
[SID857395]
 High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]NFKB1 gene product [Homo sapiens] [gi:34577122]
View
41
[SID857395]
 CYP2C19 Assay [AID778, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
View
42
[SID857395]
 CYP2C19 Assay [AID778, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
View
43
[SID857395]
 Primary Cell-based High Throughput Screening assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1) [AID522, Type: screening]NR5A1 gene product [Homo sapiens] [gi:20070193]
View
44
[SID857395]
 Primary Cell-based High Throughput Screening assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1) [AID522, Type: screening]NR5A1 gene product [Homo sapiens] [gi:20070193]
View
45
[SID857395]
 Primary Cell-based High Throughput Screening assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1) [AID522, Type: screening]NR5A1 gene product [Homo sapiens] [gi:20070193]
View
46
[SID857395]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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47
[SID857395]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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48
[SID857395]
Potency 2.6122qHTS Assay for Modulators of miRNAs and/orActivators of miR-21 [AID2288, Type: confirmatory]
View
49
[SID857395]
Potency 11.6891Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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50
[SID857395]
Potency 13.1154Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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