Bookmark and Share
SANT-1 (CID 6878030) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(6)
 
 
Inactive(129)
 
 
Inconclusive(7)
 
 
Unspecified(3)
 
 
Top Targets:
HSD10-like SD..(4)
 
 
Pyr redox dim(4)
 
 
PIKKc TOR(4)
 
 
7TM GPCR Srx(4)
 
 
P53(3)
 
 
BioAssay Types:
Confirmatory(125)
 
 
 
 
Screening(11)
 
 
Literature(9)
 
 
 
 
BioActivity Types:
Potency(123)
 
 
 
 
IC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 134    Data Row: 145   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103596001]
IC50 0.00474Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assay [AID494009, Type: Literature]
View
2
[SID103596001]
IC50 0.02Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assay [AID351761, Type: Literature]Sonic hedgehog protein [gi:6094284]
View
3
[SID103596001]
IC50 0.025Inhibition of Smoothened transfected in HEK293 cells by binding assay [AID494010, Type: Literature]
View
4
[SID26753181]
Potency 10qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
5
[SID90341472]
Potency 16.8336qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
View
6
[SID90341472]
Potency 39.8107qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID488953, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
View
7
[SID103596001]
Inhibition of hair growth in C3H/HeN mouse model assessed as inhibition of hair growth after 14 days [AID494011, Type: Literature]
View
8
[SID103596001]
Lipophilicity, log D of the compound [AID453203, Type: Literature]
View
9
[SID103596001]
Permeability in human skin after 48 hrs by Franz cell permeability assay [AID453204, Type: Literature]
View
10
[SID90341472]
Potency 3.6624HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Potentiators [AID488982, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
View
11
[SID26753181]
Potency 10qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
12
[SID26753181]
Potency 17.7828qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
View
13
[SID26753181]
Potency 19.9526qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
View
14
[SID26753181]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1 [AID900, Type: confirmatory]caspase-1 isoform alpha precursor [Homo sapiens] [gi:15431328]
View
15
[SID90341472]
Potency qHTS screen for enhancers of Arylsulfatase A (ASA1): LOPAC Validation Assay [AID720538, Type: confirmatory]arylsulfatase A [Homo sapiens] [gi:220983390]
View
16
[SID90341472]
Potency qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2 [AID488837, Type: confirmatory]eyes absent homolog 2 isoform a [Homo sapiens] [gi:26667227]
View
17
[SID26753181]
Potency qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent) [AID1476, Type: confirmatory]Chain A, Crystal Structure Of Cruzain Covalently Bound To A Purine Nitrile [gi:281307097]
View
18
[SID26753181]
Potency qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent) [AID1478, Type: confirmatory]Chain A, Crystal Structure Of Cruzain Covalently Bound To A Purine Nitrile [gi:281307097]
View
19
[SID26753181]
Potency qHTS Assay for Inhibitors of Human alpha-Galactosidase at pH 4.5. [AID1467, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
View
20
[SID26753181]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate [AID2107, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
View