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STK192375 (CID 6860029) - Compound BioActivity Data
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BioActivity Outcomes:
Active(91)
 
 
Inactive(628)
 
 
Inconclusive(20)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(48)
 
 
 
Bcl-2 like(11)
 
 
alkPPc(11)
 
 
 
G-alpha(8)
 
 
 
Tryp SPc(8)
 
 
BioAssay Types:
Screening(497)
 
 
 
 
 
Confirmatory(221)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(146)
 
 
 
 
 
IC50(47)
 
 
 
 
EC50(14)
 
 
 
AC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 673    Data Row: 741   Total Pages: 38   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14731604]
EC50 0.28Counter Screen for Luciferase-based Assay Positives [AID773, Type: confirmatory]
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2
[SID14731604]
Absolute IC50 (XBP1) 0.35XBP1 DR counterscreen for CHOP [AID504313, Type: confirmatory]XBP1 [Homo sapiens] [gi:47678753]
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3
[SID14731604]
EC50 1.34887Image-based HTS for Selective Agonists of GPR55 [AID1961, Type: confirmatory]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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4
[SID14731604]
Potency 1.4581A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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5
[SID14731604]
AC50_uM 1.604Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
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6
[SID14731604]
AC50_uM 1.707ATP-based Luminescence in the Absence of Cytokines Measured in Cell-Based System Using Plate Reader - 2061-06_Inhibitor_Dose_CherryPick [AID463229, Type: confirmatory]
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7
[SID14731604]
EC50 2.105Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity [AID1902, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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8
[SID14731604]
EC50 2.464Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
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9
[SID14731604]
EC50 4.728Luminescence Microorganism-Based Dose Response HTS to Identify Compounds Cytotoxic to Streptococcus [AID1915, Type: confirmatory]
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10
[SID14731604]
Potency 5.6234qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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11
[SID14731604]
Potency 5.8048qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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12
[SID14731604]
IC50_Artemis_Mean 5.84Dose Response confirmation of small molecule inhibitors originally identified via uHTS of Artemis endonuclease activity via a fluorescence intensity assay [AID720701, Type: confirmatory]protein artemis isoform a [Homo sapiens] [gi:76496497]
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13
[SID14731604]
Potency 6.3096qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP) [AID1688, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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14
[SID14731604]
Potency 7.0795qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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15
[SID14731604]
IC50 7.25High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media [AID449762, Type: confirmatory]
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16
[SID14731604]
Potency 7.3078qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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17
[SID14731604]
IC50 8.02High Throughput Screen to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1626, Type: confirmatory]
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18
[SID14731604]
Potency 8.9125qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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19
[SID14731604]
Potency 8.9125qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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20
[SID14731604]
EC50 9.47Luminescent HTS for small molecule inhibitors of MT1-MMP transcription [AID618, Type: confirmatory]matrix metalloproteinase 1, partial [Homo sapiens] [gi:6690534]
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