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BioActivity Data for Compound fluorene (CID 6853)

BioActivity Outcomes:
Active(3)
 
 
Inactive(199)
 
 
Inconclusive(15)
 
 
Unspecified(5)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD AR(16)
 
 
NR LBD ER(16)
 
 
NR LBD Fxr(10)
 
 
NR LBD GR(10)
 
 
 
BioAssay Types:
Confirmatory(155)
 
 
 
 
Summary(48)
 
 
 
 
Literature(4)
 
 
BioAssay Categories:
Toxicity(22)
 
 
 
 
 
ADME(1)
 
 
Cell-based(1)
 
 
BioActivity Types:
Potency(191)
 
 
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 128    Data Row: 222   Total Pages: 12   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210889]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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2
[SID144210889]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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3
[SID144210889]
TR Potency (uM) 66.0073qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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4
[SID103179261]
EC50 71Antiviral activity against BVDV infected in MDBK cells assessed as reduction in viral induced cell destruction by MTT assay [AID318336, Type: Literature]
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5
[SID103179261]
CC50 100Cytotoxicity against mock-infected MDBK cells by LDH method [AID318337, Type: Literature]
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6
[SID103179261]
Aqueous solubility [AID19262, Type: Literature]
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7
[SID103179261]
Octanol-water partition coefficient, log P of the compound [AID603957, Type: Literature]
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8
[SID26757469]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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9
[SID26757469]
Potency qHTS assay for cell viability of the p53RE-bla HCT-116 cell line [AID743292, Type: confirmatory]
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10
[SID26757469]
Potency qHTS assay for cell viability of HEK293 cells [AID743288, Type: confirmatory]
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11
[SID26757469]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity - cell viability counter screen [AID720653, Type: confirmatory]
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12
[SID144209338]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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13
[SID144209338]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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14
[SID144209338]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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15
[SID144209338]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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16
[SID144209338]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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17
[SID144210889]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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18
[SID72745]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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19
[SID72745]
NCI Yeast Anticancer Drug Screen. Data for the bub3 strain [AID167, Type: other]
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20
[SID72745]
NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
View