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3,6-diamino-10-methylacridinium (CID 6842) - Compound BioActivity Data
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BioActivity Outcomes:
Active(173)
 
 
Inactive(307)
 
 
Inconclusive(67)
 
 
Unspecified(63)
 
 
Top Targets:
7TM GPCR Srx(12)
 
 
 
7TM GPCR Srsx(11)
 
 
 
 
Troponin(6)
 
 
 
ABCC CFTR1(5)
 
 
 
NR DBD CAR(4)
 
 
 
BioAssay Types:
Screening(240)
 
 
 
 
Confirmatory(190)
 
 
 
 
 
Literature(124)
 
 
 
 
 
BioActivity Types:
Potency(165)
 
 
 
 
 
IC50(9)
 
 
 
AC50(4)
 
 
EC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 495    Data Row: 610   Total Pages: 31   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26748314]
Potency 0.0338Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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2
[SID26748314]
Potency 0.0478Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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3
[SID93576781]
AbsAC40_uM 0.116High Content Cell-Based Imaging Primary HTS to Identify Small Molecules Involved in X-Chromosome Reactivation and Reprogramming Measured in Cell-Based System Using Imaging - 7015-01_Activator_Dose_CherryPick_Activity [AID743394, Type: confirmatory]
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4
[SID93576781]
AbsAC35_uM 0.19Identification of Small Molecule Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Delta508 Mutation Function in Fischer Rat Thyroid (FRT) Cells. Measured in Cell-Based System Using Plate Reader - 7017-02_Other_Dose_CherryPick_Activity [AID743402, Type: confirmatory]
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5
[SID93576781]
AbsAC40_uM 0.378High Content Cell-Based Imaging Primary HTS to Identify autofluorescent compounds using cells not inducing Measured in Cell-Based System Using Imaging - 7015-02_Activator_Dose_CherryPick_Activity [AID743396, Type: confirmatory]
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6
[SID93576781]
AC50_uM 0.415C-LANA FP assay Measured in Biochemical System Using Plate Reader - 2117-01_Inhibitor_Dose_CherryPick_Activity [AID504725, Type: confirmatory]LANA [Human herpesvirus 8] [gi:312275222]
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7
[SID26748314]
Potency 0.5623Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504848, Type: confirmatory]
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8
[SID93576781]
EC50 0.57583Counterscreen for IDE activators: Fluorescence polarization-based biochemical high throughput dose response assay to identify fluorescent artifacts and/or optically active compounds [AID588442, Type: confirmatory]
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9
[SID26748314]
Potency 0.6334qHTS Fluorescence Polarization (FP) Assay for Inhibitors of MLL CXXC domain - DNA interaction: Fluorescein FP [AID624160, Type: confirmatory]
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10
[SID93576781]
Potency 0.6702qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
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11
[SID26748314]
Potency 0.7943Quantitative High-Throughput Screen for Regulators of Epigenetic Control [AID1865, Type: confirmatory]
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12
[SID26748314]
Potency 1Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504850, Type: confirmatory]
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13
[SID93576781]
AbsAC1000_uM 1.003In vivo-based yeast HTS to detect compounds rescuing yeast growth/survival of Plasmodium Falciparum HSP40-mediated toxicity Measured in Whole Organism System Using Plate Reader - 2120-01_Inhibitor_Dose_CherryPick_Activity [AID540271, Type: confirmatory]HSP40, subfamily A, putative [Plasmodium falciparum 3D7] [gi:124809271]
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14
[SID26748314]
Potency 1.2589qHTS Assay for Inhibitors of BRCT-Phosphoprotein Interaction (Green Fluorophore) [AID875, Type: confirmatory]Chain A, Solution Structure Of The Brct-C Domain From Human Brca1 [gi:159162802]
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15
[SID93576781]
Potency 1.4125qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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16
[SID93576781]
Potency 1.4581Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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17
[SID93576781]
Potency 1.636Nrf2 qHTS screen for inhibitors: Nrf2 A549 ARE-Fluc Confirmation Assay for Hit Validation [AID720524, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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18
[SID26748314]
Potency 1.8106S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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19
[SID93576781]
AbsAC35_uM 2.2HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Other_Dose_CherryPick_Activity_Set2 [AID743395, Type: confirmatory]
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20
[SID93576781]
AC50_uM 2.308C-LANA Counter Screen: DNA intercalators Measured in Biochemical System Using Plate Reader - 2117-02_Inhibitor_Dose_CherryPick_Activity_Set2 [AID504727, Type: confirmatory]LANA [Human herpesvirus 8] [gi:312275222]
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