delphinidin (CID 68245) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Unspecified(4)
 
 
Top Targets:
Glyoxalase I(1)
 
 
BioAssay Types:
Literature(6)
 
 
 
BioActivity Types:
IC50(3)
 
 
 
SAR
Target summary
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103724265]
IC50 1.9Inhibition of human recombinant glyoxalase 1 assessed as S-D-lactoylglutathione after 15 mins by spectrophotometric analysis [AID515620, Type: Literature]Lactoylglutathione lyase [gi:134039205]
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2
[SID103724265]
IC50 40Antiproliferative activity against human HL60 cells after 48 hrs by MTS assay [AID515622, Type: Literature]
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3
[SID103724265]
IC50 80Antiproliferative activity against human HL60 cells after 24 hrs by MTS assay [AID515621, Type: Literature]
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4
[SID103724265]
 Antiproliferative activity against human HL60 cells at up to 100 uM by MTS assay [AID515623, Type: Literature]
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5
[SID103724265]
 Induction of apoptosis in human HL60 cells assessed as nucleosomal DNA fragmentation at up to 100 uM using ethidium bromide staining by agarose gel electrophoresis [AID515625, Type: Literature]
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6
[SID103724265]
 Induction of apoptosis in human HL60 cells assessed as nucleosomal DNA fragmentation after 48 hrs using ethidium bromide staining by agarose gel electrophoresis [AID515626, Type: Literature]
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