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Guanosine Monophosphate (CID 6804) - Compound BioActivity Data
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BioActivity Outcomes:
Active(16)
 
 
Unspecified(2)
 
 
Top Targets:
PRTases typeI(9)
 
 
GGDEF(2)
 
 
BioAssay Types:
Literature(16)
 
 
 
Confirmatory(1)
 
 
BioActivity Types:
Kd(6)
 
 
Ki(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 7    Data Row: 18   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46393444]
Ki 0.5Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Response Regulator Pled In Complex With C-digmp [gi:56966618]
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2
[SID46394156]
Kd 4.5Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Bacillus Subtilis Xanthine Phosphoribosyltransferase In Complex With Guanosine 5'-monophosphate (gmp) [gi:110591504]
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3
[SID46394156]
Kd 4.5Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Bacillus Subtilis Xanthine Phosphoribosyltransferase In Complex With Guanosine 5'-monophosphate (gmp) [gi:110591504]
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4
[SID103191006]
Ki 4.5Binding affinity to Escherichia coli XGPRT [AID767229, Type: Literature]
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5
[SID46393006]
Kd 7.1Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Toxoplasma Gondii Hypoxanthine-Guanine Phosphoribosyltransferase Gmp Complex [gi:6435648]
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6
[SID46393006]
Kd 7.1Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Toxoplasma Gondii Hypoxanthine-Guanine Phosphoribosyltransferase Gmp Complex [gi:6435648]
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7
[SID46393006]
Kd 7.1Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Toxoplasma Gondii Hypoxanthine-Guanine Phosphoribosyltransferase Gmp Complex [gi:6435649]
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8
[SID46393006]
Kd 7.1Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Toxoplasma Gondii Hypoxanthine-Guanine Phosphoribosyltransferase Gmp Complex [gi:6435649]
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9
[SID103191006]
Km 18Michaelis-Menten constant (Km) for guanylate kinase was determined [AID75475, Type: confirmatory]
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10
[SID46391986]
Ki 526Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of E.Coli Hprt-Gmp Complex [gi:23200065]
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11
[SID46391986]
Ki 526Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of E.Coli Hprt-Gmp Complex [gi:23200065]
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12
[SID46393137]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Crystal Structure Of Transglutaminase 3 In Complex With Bound Gmp: Structural Basis For Alteration In Nucleotide Specificity [gi:48425682]
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13
[SID46393444]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: other]Chain A, Response Regulator Pled In Complex With C-digmp [gi:56966618]
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14
[SID46394156]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Bacillus Subtilis Xanthine Phosphoribosyltransferase In Complex With Guanosine 5'-monophosphate (gmp) [gi:110591504]
View
15
[SID46393006]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Toxoplasma Gondii Hypoxanthine-Guanine Phosphoribosyltransferase Gmp Complex [gi:6435648]
View
16
[SID46391986]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Crystal Structure Of E.Coli Hprt-Gmp Complex [gi:23200065]
View
17
[SID103191006]
Ki 120Inhibition of Escherichia coli recombinant XGPRT mutant expressed in Escherichia coli SPhi606 using guanine as substrate by spectrophotometric analysis [AID767225, Type: Literature]
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18
[SID103191006]
Ki 526Inhibition of Escherichia coli HPRT expressed in Escherichia coli SPhi606 using hypoxanthine as substrate by spectrophotometric analysis [AID767224, Type: Literature]
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