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5-fluoroindole (CID 67861) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(6)
 
 
Inconclusive(1)
 
 
Unspecified(3)
 
 
Top Targets:
M1 LTA4H(2)
 
 
BioAssay Types:
Literature(4)
 
 
 
BioActivity Types:
IC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 10    Data Row: 10   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103680600]
IC50 1000Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE [AID420374, Type: Literature]Leukotriene A-4 hydrolase [gi:126353]
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2
[SID103680600]
IC50 2000Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupole mass spectrometry [AID420375, Type: Literature]Leukotriene A-4 hydrolase [gi:126353]
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3
[SID103680600]
Solubility in methanol [AID420373, Type: Literature]
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4
[SID396179]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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5
[SID396179]
NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
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6
[SID396179]
NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
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7
[SID396179]
NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
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8
[SID396179]
NCI Yeast Anticancer Drug Screen. Data for the bub3 strain [AID167, Type: other]
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9
[SID396179]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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10
[SID103680600]
IC50 Inhibition of ionomycin-stimulated LTB4 production in human whole blood treated 15 mins prior to ionomycin challenge measured after 30 mins of stimulation by enzyme-linked immunosorbent assay [AID420376, Type: Literature]
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