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BioActivity Data for Compound Cystine (CID 67678)

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BioActivity Outcomes:
Inactive(113)
 
 
Inconclusive(13)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
 
NR LBD TR(5)
 
 
NR LBD VDR(5)
 
 
 
BioAssay Types:
Confirmatory(95)
 
 
 
Summary(24)
 
 
 
Screening(7)
 
 
Literature(3)
 
 
BioActivity Types:
Potency(110)
 
 
 
AC50(3)
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 123    Data Row: 129   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103723744]
IC50 2140Cytotoxicity against drug-resistant human KBV1 cells expressing P-gp incubated for 72 hrs by MTT assay [AID695876, Type: Literature]
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2
[SID103723744]
IC50 3120Cytotoxicity against human KB-3-1 cells incubated for 72 hrs by MTT assay [AID695877, Type: Literature]
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3
[SID103723744]
Resistance index, ratio of IC50 for human KB-3-1 cells to IC50 for drug-resistant human KBV1 cells expressing P-gp [AID695851, Type: Literature]
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4
[SID170465457]
Ac50 0.05563qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, blue channel [AID1117314, Type: confirmatory]
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5
[SID170465457]
Ac50 0.0624179qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
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6
[SID170465457]
Ac50 0.0881677qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel [AID1117310, Type: confirmatory]
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7
[SID29217764]
Potency 22.3872qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
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8
[SID29217764]
Potency 22.3872qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens] [gi:56550039]
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9
[SID29217764]
Potency 29.9349qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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10
[SID29217764]
Potency qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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11
[SID29217764]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide [AID1766, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
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12
[SID29217764]
Potency qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM) [AID2528, Type: confirmatory]Bloom syndrome protein isoform 1 [Homo sapiens] [gi:4557365]
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13
[SID29217764]
Potency qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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14
[SID29217764]
qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Coupling assay counterscreen [AID2472, Type: screening]glyceraldehyde-3-phosphate dehydrogenase isoform 1 [Homo sapiens] [gi:7669492]
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15
[SID170465457]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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16
[SID170465457]
Ratio Potency (uM) qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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17
[SID29217764]
Potency qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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18
[SID29217764]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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19
[SID29217764]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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20
[SID29217764]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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