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MLS000106837 (CID 672470) - Compound BioActivity Data
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BioActivity Outcomes:
Active(82)
 
 
Inactive(767)
 
 
Inconclusive(35)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(48)
 
 
 
Bcl-2 like(14)
 
 
 
alkPPc(14)
 
 
DSPc(14)
 
 
 
Tryp SPc(11)
 
 
BioAssay Types:
Screening(573)
 
 
 
 
 
Confirmatory(287)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(167)
 
 
 
 
 
IC50(58)
 
 
 
 
EC50(16)
 
 
 
AC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 805    Data Row: 886   Total Pages: 45   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID7974300]
AC50_uM 0.356Inhibitors of Mycobacterium tuberculosis UDP-galactopyranose mutase (UGM) enzyme Measured in Biochemical System Using Plate Reader - 2105-02_Inhibitor_Dose_CherryPick_Activity [AID540359, Type: confirmatory]UDP-galactopyranose mutase [Mycobacterium tuberculosis H37Rv] [gi:15610945]
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2
[SID7974300]
AC50_uM 0.572C-LANA FP assay Measured in Biochemical System Using Plate Reader - 2117-01_Inhibitor_Dose_CherryPick_Activity [AID504725, Type: confirmatory]LANA [Human herpesvirus 8] [gi:312275222]
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3
[SID7974300]
AC50_uM 0.728C-LANA Counter Screen: DNA intercalators Measured in Biochemical System Using Plate Reader - 2117-02_Inhibitor_Dose_CherryPick_Activity_Set2 [AID504727, Type: confirmatory]LANA [Human herpesvirus 8] [gi:312275222]
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4
[SID7974300]
Potency 3.9811qHTS Assay for Inhibitors of BRCT-Phosphoprotein Interaction (Green Fluorophore) [AID875, Type: confirmatory]Chain A, Solution Structure Of The Brct-C Domain From Human Brca1 [gi:159162802]
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5
[SID7974300]
EC50 4.946Counterscreen for IDE activators: Fluorescence polarization-based biochemical high throughput dose response assay to identify fluorescent artifacts and/or optically active compounds [AID588442, Type: confirmatory]
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6
[SID7974300]
Potency 7.9433qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1: Spectroscopic Profiling in AFC Spectral Region [AID923, Type: confirmatory]
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7
[SID7974300]
Potency 8.9125qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
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8
[SID7974300]
Potency 8.9125qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens] [gi:56550039]
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9
[SID7974300]
IC50_Mean 11.003Concentration-Response Confirmation Assays for HCS to Identify Inhibitors of Dynein Mediated Cargo Transport on Microtubules [AID463136, Type: confirmatory]
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10
[SID7974300]
EC50 13.7Dose Response validation of Activators of Apaf-1 using a Fluorescent Interference Counterscreen assay [AID588592, Type: confirmatory]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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11
[SID7974300]
Potency 50.1187qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
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12
[SID7974300]
IC50_Mean 87.4Dose response confirmation of uHTS hits for Apaf-1 in a Fluorescent assay [AID588524, Type: confirmatory]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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13
[SID7974300]
Single concentration confirmation of uHTS Fluorescent assay for identification of inhibitors of Apaf-1 [AID504614, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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14
[SID7974300]
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493008, Type: screening]cardiac alpha tropomyosin [Sus scrofa] [gi:1927]
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15
[SID7974300]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ LAP4_MLPCN. [AID2023, Type: screening]LAP4 [Saccharomyces cerevisiae] [gi:486173]
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16
[SID7974300]
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS [AID504660, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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17
[SID7974300]
uHTS Fluorescent assay for identification of inhibitors of Apaf-1 [AID489030, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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18
[SID7974300]
Single concentration validation of uHTS inhibitor hits from DNMT1 for spectral interference using a Fluorescent Molecular Beacon assay [AID602387, Type: screening]
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19
[SID7974300]
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput screening assay to identify nonselective agonists [AID651787, Type: screening]guanine nucleotide-binding protein subunit alpha-15 [Homo sapiens] [gi:156104883]
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20
[SID7974300]
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput screening assay to identify nonselective Ga16 antagonists [AID651952, Type: screening]guanine nucleotide-binding protein subunit alpha-15 [Homo sapiens] [gi:156104883]
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