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BioActivity Data for Compound Spectrum_000080 (CID 6710614)

BioActivity Outcomes:
Active(12)
 
 
Inactive(152)
 
 
Inconclusive(2)
 
 
Top Targets:
NR LBD RAR(6)
 
 
NR LBD COUP-T..(5)
 
 
7tm 4(5)
 
 
NR LBD RXR li..(4)
 
 
 
NR LBD VDR(4)
 
 
BioAssay Types:
Screening(82)
 
 
 
Confirmatory(72)
 
 
 
 
Literature(5)
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(2)
 
 
Toxicity(2)
 
 
Cell-based(71)
 
 
 
BioActivity Types:
Potency(72)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 89    Data Row: 166   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID90341476]
Potency 0.013Nrf2 qHTS screen for inhibitors: Validation [AID493153, Type: confirmatory] [geneid:4780]
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2
[SID90341476]
Potency 0.013Nrf2 qHTS screen for inhibitors: Validation [AID493153, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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3
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_29, Type: screening]glucocorticoid receptor isoform gamma [Homo sapiens] [gi:66528677]
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4
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_62, Type: screening]thyroid hormone receptor beta [Homo sapiens] [gi:40806162]
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5
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_37, Type: screening]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
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6
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_36, Type: screening]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
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7
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_14, Type: screening]oxysterols receptor LXR-beta isoform 1 [Homo sapiens] [gi:85362735]
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8
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277, Type: screening]
View
9
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_38, Type: screening]nuclear receptor subfamily 5 group A member 2 isoform 2 [Homo sapiens] [gi:4504343]
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10
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_56, Type: screening]retinoic acid receptor RXR-alpha isoform a [Homo sapiens] [gi:4506755]
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11
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_57, Type: screening]retinoic acid receptor RXR-alpha isoform a [Homo sapiens] [gi:4506755]
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12
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_30, Type: screening]mineralocorticoid receptor isoform 2 [Homo sapiens] [gi:260656020]
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13
[SID174007386]
Potency 0.0421qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (3D7) proliferation [AID743344, Type: confirmatory]
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14
[SID90341476]
Potency 4.7444qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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15
[SID174007386]
Potency 8.4071qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation [AID743345, Type: confirmatory]
View
16
[SID92124059]
A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme MbtI [AID493033, Type: other]Isochorismate synthase/isochorismate-pyruvate lyase mbtI [gi:81706979]
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17
[SID90341476]
Potency qHTS for Inhibitors of ATXN expression: Validation [AID588378, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
View
18
[SID90341476]
Potency qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
View
19
[SID90341476]
Potency qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID488953, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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20
[SID90341476]
Potency qHTS Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter [AID463106, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
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