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Spectrum_000080 (CID 6710614) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(12)
 
 
Inactive(151)
 
 
Inconclusive(2)
 
 
Top Targets:
NR LBD RAR(6)
 
 
NR LBD COUP-T..(5)
 
 
PIKKc TOR(4)
 
 
NR LBD VDR(4)
 
 
Pyr redox dim(4)
 
 
BioAssay Types:
Screening(80)
 
 
 
Confirmatory(71)
 
 
 
 
Literature(7)
 
 
BioActivity Types:
Potency(71)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 88    Data Row: 165   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID90341476]
Potency 0.013Nrf2 qHTS screen for inhibitors: Validation [AID493153, Type: confirmatory] [geneid:4780]
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2
[SID90341476]
Potency 0.013Nrf2 qHTS screen for inhibitors: Validation [AID493153, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
View
3
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_29, Type: screening]glucocorticoid receptor isoform gamma [Homo sapiens] [gi:66528677]
View
4
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_62, Type: screening]thyroid hormone receptor beta [Homo sapiens] [gi:40806162]
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5
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_36, Type: screening]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
View
6
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_37, Type: screening]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
View
7
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_14, Type: screening]oxysterols receptor LXR-beta isoform 1 [Homo sapiens] [gi:85362735]
View
8
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277, Type: screening]
View
9
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_38, Type: screening]nuclear receptor subfamily 5 group A member 2 isoform 2 [Homo sapiens] [gi:4504343]
View
10
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_56, Type: screening]retinoic acid receptor RXR-alpha [Homo sapiens] [gi:4506755]
View
11
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_57, Type: screening]retinoic acid receptor RXR-alpha [Homo sapiens] [gi:4506755]
View
12
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_30, Type: screening]mineralocorticoid receptor isoform 2 [Homo sapiens] [gi:260656020]
View
13
[SID174007386]
Potency 0.0421qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (3D7) proliferation [AID743344, Type: confirmatory]
View
14
[SID90341476]
Potency 4.7444qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
View
15
[SID174007386]
Potency 8.4071qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation [AID743345, Type: confirmatory]
View
16
[SID174007386]
Potency qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation (Rep 2) [AID743346, Type: confirmatory]
View
17
[SID174007386]
Potency qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (HB3) proliferation [AID743347, Type: confirmatory]
View
18
[SID17404776]
In Vivo Angiogenesis Assay for HTS [AID732, Type: screening]
View
19
[SID90341476]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
View
20
[SID90341476]
Potency qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay [AID588349, Type: confirmatory]
View
21
[SID92124059]
A screen for compounds that inhibit liver stage malaria [AID624349, Type: other]
View
22
[SID163564167]
Fluorescence-based counterscreen assay of HCV NS3 helicase-DNA binding inhibitors in LOPAC1280: biochemical high-throughput screening assay to identify compounds that enhance or quench fluorescence of a Cy5-DNA-NS3h complex [AID687037, Type: Literature]
View
23
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_46, Type: screening]retinoic acid receptor alpha isoform 1 [Homo sapiens] [gi:4506419]
View
24
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_47, Type: screening]retinoic acid receptor alpha isoform 1 [Homo sapiens] [gi:4506419]
View
25
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_50, Type: screening]retinoic acid receptor gamma isoform 1 [Homo sapiens] [gi:4506423]
View
26
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_51, Type: screening]retinoic acid receptor gamma isoform 1 [Homo sapiens] [gi:4506423]
View
27
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_52, Type: screening]nuclear receptor ROR-alpha isoform c [Homo sapiens] [gi:4506577]
View
28
[SID87219224]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_55, Type: screening]retinoic acid receptor RXR-alpha [Homo sapiens] [gi:4506755]
View
29
[SID92303719]
LOPAC Circadian Assay [AID2774, Type: screening]
View
30
[SID53777319]
96-well format Chlamydomonas reinhardtii Algae Gravitaxis Assay to measure the difference in the absorbance between the small compact plug of WT swimming algae versus the MUT algae lacking cilia. [AID463189, Type: screening]
View
31
[SID90341476]
Potency qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
View
32
[SID90341476]
Potency qHTS for compounds that reverse cellular toxicity of Amyloid beta (A-beta) peptide in yeast: LOPAC Validation Assay [AID720559, Type: confirmatory]Amyloid beta A4 protein [gi:112927]
View
33
[SID121361031]
A screen for compounds that inhibit nucleocapsid/RNA interactions in Rift Valley Fever Virus [AID651828, Type: other]Nucleoprotein [gi:127925]
View
34
[SID90341476]
Potency HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Hit Validation in HTRF [AID624455, Type: confirmatory]dopamine D1 receptor [Homo sapiens] [gi:299681]
View
35
[SID90341476]
Potency qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
View
36
[SID50110976]
Potency qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
View
37
[SID50110977]
Potency qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
View
38
[SID90341476]
Potency qHTS of alpha-syn Inhibitors [AID652106, Type: confirmatory]Alpha-synuclein [gi:586067]
View
39
[SID90341476]
Potency qHTS of Nrf2 Activators: LOPAC Validation [AID624149, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
View
40
[SID92124059]
Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection [AID720717, Type: other]ORF 73 [Human herpesvirus 8 type M] [gi:1718329]
View
41
[SID90341476]
Potency qHTS of GLP-1 Receptor Agonists: LOPAC Validation [AID624148, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
View
42
[SID90341476]
Potency qHTS for Activators of Parkin Expression: LOPAC Validation Assay (NLuc Reporter) [AID720572, Type: confirmatory]Parkin [Homo sapiens] [gi:3063388]
View
43
[SID90341476]
Potency qHTS for Activators of Parkin Expression: LOPAC Validation Assay (FLuc Reporter) [AID720573, Type: confirmatory]Parkin [Homo sapiens] [gi:3063388]
View
44
[SID17404776]
HTS for Tumor Hsp90 Inhibitors [AID429, Type: screening]90-kda heat shock protein beta HSP90 beta [Homo sapiens] [gi:4261762]
View
45
[SID90341476]
Potency qHTS validation assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID485366, Type: confirmatory]beta-2 adrenergic receptor [Homo sapiens] [gi:4501969]
View
46
[SID90341476]
Potency HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Agonists [AID488981, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
View
47
[SID90341476]
Potency HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Potentiators [AID488982, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
View
48
[SID90341476]
Potency HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Antagonists [AID488983, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
View
49
[SID90341476]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: Diaphorase-coupled assay [AID743205, Type: confirmatory]glucokinase isoform 1 [Homo sapiens] [gi:4503951]
View
50
[SID90341476]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: ADP-Glo assay [AID743206, Type: confirmatory]glucokinase isoform 1 [Homo sapiens] [gi:4503951]
View