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Cantharidin (CID 6708701) - Compound BioActivity Data
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BioActivity Outcomes:
Active(81)
 
 
Inactive(445)
 
 
Inconclusive(47)
 
 
Unspecified(9)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
7TM GPCR Srsx(17)
 
 
 
NR LBD PPAR(8)
 
 
 
 
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
 
BioAssay Types:
Screening(336)
 
 
 
 
Confirmatory(188)
 
 
 
 
 
Summary(24)
 
 
 
 
Literature(15)
 
 
 
BioActivity Types:
Potency(183)
 
 
 
 
 
IC50(13)
 
 
 
EC50(9)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 531    Data Row: 582   Total Pages: 30   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144203877]
Potency-Replicate_1 0.1012qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144203877]
Ratio Potency (uM) 0.154406qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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3
[SID57264299]
EC50_MICROM 0.18Confirmation dose response of additional hit compounds from high-throughput yeast screen for caloric restriction mimetics that inhibit age-related superoxide. [AID504927, Type: confirmatory]
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4
[SID57264299]
IC50 0.23916Counterscreen for inhibitors of PP1: fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Protein Phosphatase 5 (PP5) [AID2422, Type: confirmatory]PPP5C protein, partial [Homo sapiens] [gi:37589898]
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5
[SID57264299]
IC50 0.2716Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Protein Phosphatase 1 (PP1) [AID2403, Type: confirmatory]serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform 3 [Homo sapiens] [gi:56790945]
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6
[SID57264299]
Potency 0.5012qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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7
[SID144203877]
Potency-Replicate_1 0.5693qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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8
[SID144203877]
Potency-Replicate_1 0.9023qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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9
[SID144203877]
Ratio Potency (uM) 0.909931qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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10
[SID144203877]
ATAD5 Potency (uM) 1.01235qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
View
11
[SID57264299]
Potency 1.122qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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12
[SID57264299]
Potency 1.2589qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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13
[SID144203877]
Potency-Replicate_1 1.2853qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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14
[SID57264299]
Potency 1.4581qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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15
[SID57264299]
Potency 1.4581qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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16
[SID57264299]
Potency 1.5849qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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17
[SID144203877]
Potency-Replicate_1 1.6045qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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18
[SID57264299]
Potency 1.7783qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor, partial [Homo sapiens] [gi:1724069]
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19
[SID144203877]
Ratio Potency (uM) 1.81555qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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20
[SID57264299]
Potency 1.8526Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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