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Dienestrol (CID 667476) - Compound BioActivity Data
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BioActivity Outcomes:
Active(37)
 
 
Inactive(985)
 
 
Inconclusive(85)
 
 
Unspecified(21)
 
 
Top Targets:
7tm 4(52)
 
 
 
NR LBD ER(16)
 
 
 
 
alkPPc(14)
 
 
NR LBD PPAR(14)
 
 
 
 
Tryp SPc(13)
 
 
BioAssay Types:
Screening(624)
 
 
 
 
Confirmatory(372)
 
 
 
 
 
Literature(34)
 
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(306)
 
 
 
 
 
IC50(50)
 
 
 
EC50(14)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 977    Data Row: 1128   Total Pages: 57   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144203929]
Potency-Replicate_1 0.0003qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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2
[SID144203929]
Potency-Replicate_1 0.0006qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID144203929]
Ratio Potency (uM) 0.000810089qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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4
[SID855694]
Potency 1.4581qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID492947, Type: confirmatory]beta-2 adrenergic receptor [Homo sapiens] [gi:4501969]
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5
[SID144203929]
Potency-Replicate_1 3.2013qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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6
[SID144203929]
Ratio Potency (uM) 3.91591qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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7
[SID855694]
Potency 4.6109A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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8
[SID855694]
Potency 7.9433qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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9
[SID144203929]
Potency-Replicate_1 9.0226qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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10
[SID144203929]
Ratio Potency (uM) 10.609qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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11
[SID144203929]
Ratio Potency (uM) 10.9311qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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12
[SID855694]
EC50 13.2415Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation [AID737, Type: confirmatory]Estrogen receptor 1 [Homo sapiens] [gi:118764400]
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13
[SID170465362]
Ratio Potency (uM) 13.3322qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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14
[SID170465362]
Potency-Replicate_1 14.9589qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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15
[SID855694]
Potency 15.8489qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
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16
[SID855694]
WT IC50 20.953Chemical Genetic Screen to Identify Inhibitors of Mitochondrial Fusion - Confirmatory Screen [AID1361, Type: confirmatory]
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17
[SID855694]
Potency 25.1189qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase, partial [Homo sapiens] [gi:1832253]
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18
[SID855694]
IC50_Mean 25.6Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay [AID493003, Type: confirmatory]TPA: protein transporter TIM10 [Saccharomyces cerevisiae S288c] [gi:285809906]
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19
[SID855694]
Potency 25.929qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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20
[SID170465362]
Potency-Replicate_1 29.847qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743191, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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