Bookmark and Share
SMR000044166 (CID 663437) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(7)
 
 
Inactive(798)
 
 
Inconclusive(15)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(44)
 
 
alkPPc(16)
 
 
Bcl-2 like(12)
 
 
PTPc(9)
 
 
Tryp SPc(9)
 
 
BioAssay Types:
Screening(553)
 
 
 
 
Confirmatory(235)
 
 
 
 
 
Literature(9)
 
 
BioActivity Types:
Potency(149)
 
 
 
 
IC50(52)
 
 
 
EC50(13)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 750    Data Row: 821   Total Pages: 42   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID862214]
IC50 16TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70 [AID786, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
View
2
[SID862214]
IC50 55.1High Throughput Screening Assay for Hsp70 Inhibitors [AID583, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
View
3
[SID862214]
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors [AID633, Type: screening]estrogen receptor beta isoform 1 [Homo sapiens] [gi:10835013]
View
4
[SID862214]
HTS of Smad transcription factor inhibitors [AID630, Type: screening]mothers against decapentaplegic homolog 3 isoform 1 [Homo sapiens] [gi:5174513]
View
5
[SID862214]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
View
6
[SID862214]
Fluorescence Polarization Cell-Free Homogeneous Primary HTS to Identify Inhibitors of the LANA Histone H2A/H2B Interaction [AID2629, Type: screening]LANA [Human herpesvirus 8] [gi:139472804]
View
7
[SID862214]
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors [AID629, Type: screening]Estrogen receptor 1 [Homo sapiens] [gi:118764400]
View
8
[SID862214]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
9
[SID862214]
Potency 0.0002qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
View
10
[SID862214]
IC50 50Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation [AID733, Type: confirmatory]estrogen receptor beta isoform 1 [Homo sapiens] [gi:10835013]
View
11
[SID862214]
IC50 50Estrogen Receptor-alpha Coactivator Binding Inhibitors Dose Response Confirmation [AID713, Type: confirmatory]Estrogen receptor 1 [Homo sapiens] [gi:118764400]
View
12
[SID862214]
EC50_uM 75Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction [AID435023, Type: confirmatory]LANA [Human herpesvirus 8] [gi:139472804]
View
13
[SID862214]
Potency 89.1251HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
View
14
[SID862214]
IC50 999High Throughput Screening Assay for Hsc70 Inhibitors [AID568, Type: confirmatory]heat shock cognate 71 kDa protein isoform 2 [Homo sapiens] [gi:24234686]
View
15
[SID862214]
IC50 999High Throughput Screening Assay for Hsc70 Inhibitors [AID568, Type: confirmatory]heat shock cognate 71 kDa protein isoform 1 [Homo sapiens] [gi:5729877]
View
16
[SID862214]
Activator for delta FosB/delta FosB homodimer Measured in Biochemical System Using Plate Reader - 2072-01_Activator_SinglePoint_HTS_Activity [AID493131, Type: screening]protein fosB [Mus musculus] [gi:6679827]
View
17
[SID862214]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. [AID1439, Type: screening]guanine nucleotide-binding protein G(o) subunit alpha isoform a [Homo sapiens] [gi:10567816]
View
18
[SID862214]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. [AID1440, Type: screening]guanine nucleotide-binding protein G(o) subunit alpha isoform a [Homo sapiens] [gi:10567816]
View
19
[SID862214]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. [AID1441, Type: screening]guanine nucleotide-binding protein G(o) subunit alpha isoform a [Homo sapiens] [gi:10567816]
View
20
[SID862214]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. [AID1415, Type: screening]guanine nucleotide-binding protein G(o) subunit alpha isoform a [Homo sapiens] [gi:10567816]
View